Isolation of the compounds from antimicrobial active fraction from the stem barks of Entada spiralis Ridl

Mat So'ad, Siti Zaiton and Harun, Aiza and Mohd Hassan, Norazian and Che Mohd Ramli, Neni Kartini (2011) Isolation of the compounds from antimicrobial active fraction from the stem barks of Entada spiralis Ridl. In: IIUM Research, Invention and Innovation Exhibition (IRIIE) 2011, 9-10 February 2011, Cultural Activity Centre (CAC) and KAED Gallery IIUM.

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Abstract

Entada spiralis Ridl. which is locally known as Sintok or Beluru is a woody climber with a characteristic spiral stem. The stem bark is traditionally used as natural shampoo and body wash among Malays due to its high content of saponins and its medicinal properties. The methanol extract of the stem bark possess promising antimicrobial activity against some species of skin diseases caused microbes The extract was further fractionation with different solvent gradient and repeated test on dermatophytes were done. The most active fraction is chloroform: methanol(9:1(V/V)). From this fraction we managed to isolate five compounds. The structure elucidation of the compounds were based on spectroscopic data ( 1H and 13C NMR, HMQC, HMBC and DEPT135).

Item Type:	Conference or Workshop Item (Poster)
Additional Information:	5652/8023
Uncontrolled Keywords:	antimicrobial active fraction
Subjects:	R Medicine > RS Pharmacy and materia medica
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Pharmacy > Department of Pharmaceutical Chemistry
Depositing User:	Dr. Siti Zaiton Mat So'ad
Date Deposited:	16 Jul 2013 14:24
Last Modified:	09 Dec 2022 10:53
URI:	http://irep.iium.edu.my/id/eprint/8023

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