Biomechanical analysis of patient-specific femur model of osteogenesis imperfecta with cortical and cancellous bone

Tan, L. C. and Mat Som, Mohd Hanafi and Basarudin, Khairul Salleh and Yazid, Haniza and Daud, Ruslizam and Awang, Mohamed Saufi (2019) Biomechanical analysis of patient-specific femur model of osteogenesis imperfecta with cortical and cancellous bone. In: "6th International Conference on Applications and Design in Mechanical Engineering 2019, ICADME 2019", 26 - 27 August 2019, Penang.

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Abstract

Osteogenesis imperfecta (OI) is a fragile bone disease characterized by easy fractures. The femur consists of cortical and cancellous bone, each with different mechanical properties. Bone fractures often occur throughout patients’ lifetime. However, doctors still have no quantitative method to predict fractures. This project’s purpose is to investigate the mechanical behaviour of patient-specific OI femur from the finite element analysis. The fracture risk in daily activities (ADL) were examined. All the stress values were judged by the fracture criteria, assumed as 115 MPa. The exercises that exerted force more than 6 times of body weight could cause fractures. Cancellous bone was not affected in any case of ADL. The effects of force and stress on cancellous bone and its impact on fracture risk are negligible.

Item Type:	Conference or Workshop Item (Invited Papers)
Additional Information:	6398/79698
Uncontrolled Keywords:	Analysis of patient-specific femur model; Osteogenesis imperfecta; Cortical and cancellous bone
Subjects:	R Medicine > R Medicine (General) R Medicine > RD Surgery
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine
Depositing User:	Assoc Prof Mohamed Saufi Awang
Date Deposited:	13 Jul 2020 09:15
Last Modified:	13 Jul 2020 09:15
URI:	http://irep.iium.edu.my/id/eprint/79698

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