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In-vivo confocal microscopy: comparison of Keratocytes cell density (KCD) between Femtosecond LASIK (FS-LASIK) and Photorefractive keratectomy (PRK) at one month follow-up

Mat Rejab @ Md Rejab, Noorshazana and Hilmi, Mohd Radzi and Mohd. Kamal, Khairidzan and Md Mustafa, Md Muziman Syah (2019) In-vivo confocal microscopy: comparison of Keratocytes cell density (KCD) between Femtosecond LASIK (FS-LASIK) and Photorefractive keratectomy (PRK) at one month follow-up. In: 7th USM Ophthalmology Symposium in conjunction with the 9th Conjoint Ophthalmology Scientific Conference, 13-15 Sep 2019, Hotel Perdana, Kota Bharu, Kelantan, Malaysia.

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Abstract

Sixteen eyes of 8 participants who underwent FS-LASIK and PRK involved in this prospective nonrandomised study. Inclusion criteria includes of having moderate to high myopia (spherical equivalent, SE: - 3.25D to 9.25D).A flap was created and repositioned back after ablated in FS-LASIK, while in PRK the entire corneal epithelium was removed(flap-less)before ablated. Central corneas were scanned throughout their full thickness using HRTIII/RCM during baseline and post-operative 1 month by single examiner. Morphologic modifications of KCD were evaluated. Using image analysis, KCD was measured in cell/mm2. Two images with non-artefact were selected from each stromal layer for evaluation of KCD and the average mean was taken for analysis. KCD was manually calculated within a region of interest (ROI)set at 0.16mm2 by modification of brightness and contrast. Cells which are more illuminated and refringent were selected and analysed using Wilcoxon signed-rank and Mann-Whitney U test.

Item Type: Conference or Workshop Item (Poster)
Additional Information: 7746/79253
Uncontrolled Keywords: Keratocytes cell density, KCD, Femtosecond LASIK, FS-LASIK, Photorefractive keratectomy, PRK
Subjects: R Medicine > RE Ophthalmology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Allied Health Sciences > Department of Optometry and Visual Science
Kulliyyah of Medicine > Department of Ophthalmology
Depositing User: Dr. Md Muziman Syah Md Mustafa
Date Deposited: 28 Feb 2020 10:05
Last Modified: 28 Feb 2020 10:19
URI: http://irep.iium.edu.my/id/eprint/79253

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