Coscinium fenestratum: a review on phytochemicals and pharmacological properties

Bakhtiar, M. Taher and Amri, Mohamad Shahreen and Darnis, Deny Susanti and Abdul Kudos, Muhammad Badri and Shafawi, Anis Natasha and Yazid, Soraya Nur (2019) Coscinium fenestratum: a review on phytochemicals and pharmacological properties. In: Natural Bio-active Compounds Volume 2: Chemistry, Pharmacology and Health Care Practices. Springer, Singapore, pp. 107-126. ISBN 978-981-13-7204-9

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Abstract

Coscinium fenestratum has been used in the traditional medicine, especially in the Ayurvedic method of healing as this plant can be found vastly in the Western Ghats of India. The distribution of this plant is concentrated to the Southeast Asiaincluding Sri Lanka, India, Cambodia, Vietnam, Peninsular Malaysia, Sumatra, West Java, Borneo, Northeast of Thailand and Laos. This review is related to the phytochemicals and pharmacological effects of C. fenestratum. The major chemi- cal constituents present in this plant include alkaloids, flavonoids and steroids. The most important bio-active compound is the berberine, which is the most widely studied plant compound. This plant exerts several pharmacological effects including antidiabetic, anticancer, antibacterial, antimalarial, antioxidant, antihy- pertensive, antiulcer, neuroprotector and wound healing activities. This chapter is supported by in vitro and in vivo studies carried out from the year of 1970 to 2016, which are available from PubMed, ScienceDirect, Google Scholar and Scopus.

Item Type:	Book Chapter
Additional Information:	5209/75034
Subjects:	R Medicine > RS Pharmacy and materia medica R Medicine > RS Pharmacy and materia medica > RS192 Materia Medica-Pharmaceutical Technology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Pharmacy Kulliyyah of Pharmacy > Department of Pharmaceutical Technology Kulliyyah of Science Kulliyyah of Science > Department of Chemistry
Depositing User:	Dr Muhammad Taher
Date Deposited:	19 Nov 2019 14:48
Last Modified:	19 Nov 2019 14:48
URI:	http://irep.iium.edu.my/id/eprint/75034

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