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Neuropsychiatric Systemic Lupus Erythematosus (NPSLE) – masquerade diagnosis: a case report

Mohd Hanafi, Mohd Sharil Iman and Che' Man, Mohamad and Che Alhadi, Shahidah (2019) Neuropsychiatric Systemic Lupus Erythematosus (NPSLE) – masquerade diagnosis: a case report. Journal of Family Medicine Forecast, 2 (2). pp. 1-3. ISSN 2643-7864

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Diagnostic challenge is seen in Systemic Lupus Erythematosus (SLE) due to insidious onset, unpredictable course and broad spectrum of clinical presentation [1]. SLE can mimic other diseases manifestation and possibility not fulfilling the classification criteria at the earlier course of the disease [1]. We highlighted a case of a man, lived with diagnosis of Schizophrenia for almost 15 years subsequently revealed him suffered from neuropsychiatric lupus as he fulfilled the SLE classification criteria. His initial presentation was altered sensorium treated as acute psychosis- the tip of an iceberg to the underlying disease [2]. His multiple admissions to psychiatric ward were believed contributed by episode of lupus flare [2,3]. Necessary investigation is important to exclude another medical condition before make a diagnosis of Schizophrenia using DSM-V criteria [2]. The misdiagnosis has significantly impaired his social life and untreated disease had leads to morbidity and severe organ damage. This case emphasizes on the crucial aspect of assessing patient as a whole, follow-up the progression and re-evaluates patient’s condition for a new hint. Even though there is no cure yet for SLE, correct and early diagnosis is able to guide for individualized treatment and thus helping in good disease control that warrant better outcome [4].

Item Type: Article (Case Report)
Additional Information: 6884/74793
Uncontrolled Keywords: SLE; Schizophrenia; Neuropsychiatric lupus; Altered sensorium
Subjects: R Medicine > R Medicine (General)
R Medicine > RA Public aspects of medicine
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Medicine
Kulliyyah of Medicine > Department of Family Medicine (Effective: 1st January 2011)
Kulliyyah of Medicine > Department of Surgery
Depositing User: DR MOHAMMAD HJ. CHE' MAN
Date Deposited: 11 Oct 2019 16:26
Last Modified: 10 May 2022 10:47
URI: http://irep.iium.edu.my/id/eprint/74793

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