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Papillary thyroid cancer: Genetic alterations and molecular biomarker investigations

Abdullah, Mardiaty Iryani and Mat Junit, Sarni and Khoon, Leong Ng and Jayapalan, Jaime Jacqueline and Karikalan, Barani and Hashim, Onn (2019) Papillary thyroid cancer: Genetic alterations and molecular biomarker investigations. International Journal of Medical Sciences, 16 (3). pp. 450-460. ISSN 1449-1907

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Papillary thyroid cancer (PTC) is the most prevalent form of malignancy among all cancers of the thyroid. It is also one of the few cancers with a rapidly increasing incidence. PTC is usually contained within the thyroid gland and generally biologically indolent. Prognosis of the cancer is excellent, with less than 2% mortality at 5 years. However, more than 25% of patients with PTC developed a recurrence during a long term follow-up. The present article provides an updated condensed overview of PTC, which focuses mainly on the molecular alterations involved and recent biomarker investigations.

Item Type: Article (Journal)
Additional Information: 8443/72650
Uncontrolled Keywords: papillary thyroid cancer, molecular alteration, genetic signature, biomarker, diagnostics
Subjects: R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Allied Health Sciences
Kulliyyah of Allied Health Sciences > Department of Biomedical Science (Effective:1st July 2011)
Depositing User: Dr Mardiaty Iryani Abdullah
Date Deposited: 14 Jun 2019 17:06
Last Modified: 14 Jun 2019 17:06
URI: http://irep.iium.edu.my/id/eprint/72650

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