Investigation of porcupine bezoar extract combined with electroporation on HeLa cell

Azizulkarim, Azra Hazwanie and Abdul Jamil, Muhammad Mahadi and Tengku Ibrahim, Tengku Nadzlin and Hamdan, Salehhuddin and Baba, Sayang and Abdul Wahab, Ridhwan (2019) Investigation of porcupine bezoar extract combined with electroporation on HeLa cell. In: 8th IEEE International Conference on Control System, Computing and Engineering, ICCSCE 2018, 23-25 November 2018, PARKROYAL Penang Resort Batu Ferringhi Penang.

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Abstract

Current chemo-preventive agents will causes a long term side effects in cancer sufferer. Therefore, this research focusses on the benefits of combine both technique of Electroporation (EP) method and with natural animal extract in process to inhibit the proliferation of cancer cell, as a solution to reduce or adverse effects of orthodox drugs. The present study indicates on anti-cancer potentially of Porcupine Bezoar Extract (PBE), also known as Hystrix Brachyuran against HeLa cell. Cell viability of HeLa cell were determined after HeLa cell treated with 500 V/cm and pulse duration of 100µs before the concentration of 80.0 µg/ml of Porcupine Bezoar Extract (PBE) was added into the cell. The cell viability and cell growth were monitored up to 48 hours with comparative to untreated cell as a control group.This study result proved that by combine both technique; Electroporation (EP) and with natural animal extract Porcupine Bezoar Extract (PBE) might open the door and it has an ability in supressing the growth of HeLa cell.

Item Type:	Conference or Workshop Item (Plenary Papers)
Additional Information:	5136/72648
Uncontrolled Keywords:	Electroporation (EP), Porcupine Bezoar Extract (PBE); HeLa cell, Anti-cancer
Subjects:	Q Science > QP Physiology R Medicine > R Medicine (General) R Medicine > RM Therapeutics. Pharmacology T Technology > T Technology (General) T Technology > TP Chemical technology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Allied Health Sciences Kulliyyah of Allied Health Sciences > Department of Biomedical Science (Effective:1st July 2011)
Depositing User:	Dr Ridhwan Abdul Wahab
Date Deposited:	14 Jun 2019 17:04
Last Modified:	14 Jun 2019 17:04
URI:	http://irep.iium.edu.my/id/eprint/72648

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