Identification of phenolic compounds in crude methanolic extract of Piper sarmentosum leaves

Mustafa, Farah Farisha and Ibrahim, Maizatul Akma and Mohamad, Habsah (2017) Identification of phenolic compounds in crude methanolic extract of Piper sarmentosum leaves. In: 6th International Conference on Advancement in Science and Technology (iCAST 2017), 9th August 2017, Kuantan, Pahang. (Unpublished)

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Abstract

Herbal plants are rich sources of secondary metabolites such as phenolics which can be beneficial to improve human health. Previous studies reported that phenolic compounds could lower the risk of heart diseases, occurrence of cancers as well as microbial infections. Piper sarmentosum or locally known as Kaduk is a tropical herb plant that is well established for many traditional medicinal purposes. These benefits may depend significantly on the phenolic content. Hence, the identification of phenolic compounds in this plant is necessary. The objective of the present study was to identify the phenolic compounds in crude methanolic extract of Piper sarmentosum leaves. Total phenolic content was determined spectrometrically according to Folin-Ciocalteu procedures. The characterization of the phenolic compounds was examined using reverse phase HPLC and GC-MS analyses. The total phenolic content was found to be 142.72 mg[GAE]/g of the Kaduk leaves extract. The presences of gallic acid, tannic acid, quercetin and naringenin were identified from the RP-HPLC analysis. From GC-MS analysis, the presences of elemicine, myristicine, methyleugenol and hydrocinnamic acid were revealed. Our findings provided the evidence that crude methanolic extract of Piper sarmentosum leaves contains high content of active phenolic compounds that might have the potential to be incorporated as the basis ingredient in medicines to treat various diseases in Malaysia.

Item Type:	Conference or Workshop Item (Other)
Additional Information:	7138/71451
Uncontrolled Keywords:	Piper sarmentosum, RP-HPLC, GC-MS, plant methanol extract, phenolic compound
Subjects:	Q Science > Q Science (General) Q Science > QK Botany Q Science > QR Microbiology R Medicine > RM Therapeutics. Pharmacology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Science Kulliyyah of Science > Department of Plant Science
Depositing User:	Dr Maizatul Ibrahim
Date Deposited:	07 May 2019 14:38
Last Modified:	07 May 2019 14:38
URI:	http://irep.iium.edu.my/id/eprint/71451

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