Anti-diabetic potential of peptide from P. niruri reveals through carbohydrate hydrolyzing enzyme inhibition assay

Md Zin, Noor Hasniza and Mohd Nail, Ainul Mardhiah (2019) Anti-diabetic potential of peptide from P. niruri reveals through carbohydrate hydrolyzing enzyme inhibition assay. Science Heritage Journal (GWS), 3 (1). pp. 17-19. ISSN 2521-0858 E-ISSN 2521-0866

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Abstract

Herb Phyllanthus niruri (P. niruri) is known to have various pharmacological functions including anti-diabetic properties. In this research, protein extracts from different plant parts (leave, fruit and stem) of P. niruri were investigated for their anti-diabetic potential through α-amylase and α-glucosidase enzyme inhibition assays. For the enzyme inhibition assay, fruit was found to have the highest inhibition percentage (90.0%) against α-glucosidase followed by leave (62.6%) and stem (38.4%). The similar patterns were also recorded for the α-amylase enzyme inhibition assay, in which, fruit showed the highest inhibition percentage (64.1%) followed by leave (33.3%) and stem (18.2%). The findings of this research suggest that fruit of P. niruri is a potential plant part with regards to antidiabetic properties since it exhibits the highest inhibition activity against both α-amylase and α-glucosidase enzyme compared to leave and stem.

Item Type:	Article (Journal)
Additional Information:	6771/70806
Uncontrolled Keywords:	Diabetes mellitus, Phyllanthus niruri, α-amylase, α-glucosidase
Subjects:	Q Science > Q Science (General)
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Science Kulliyyah of Science > Department of Biotechnology
Depositing User:	Dr Noor Hasniza Md Zin
Date Deposited:	05 Mar 2019 16:22
Last Modified:	12 Jul 2019 16:04
URI:	http://irep.iium.edu.my/id/eprint/70806

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