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Comparing simultaneous versus staged resection in patients with synchronous colorectal liver metastases: case match study

Elagili, Faisal and Ozuner, Gokhan and Berber, Eren and Akyuz, Muhammet and Cem Dural, Ahmet (2014) Comparing simultaneous versus staged resection in patients with synchronous colorectal liver metastases: case match study. Journal of The American College of Surgeons, 219 (4 Supplement). e75-e76. ISSN 1072-7515

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INTRODUCTION: There is no consensus on the optimal timing of liver resection in patients with synchronous colorectal liver metastasis. METHODS: Patients undergoing hepatic resections between 2004- 2013 for synchronous colorectal liver metastases were analyzed from a prospectively maintained and institutional review board approved database. Patients who underwent simultaneous resection of a colorectal primary and hepatic metastasis in a single operation (Group I) were case-matched 1:1with patients who underwent staged operation (Group II) according to age, sex, ASA classification, size of liver lesion and number of liver lesion. RESULTS: 66 patients (33 Group I, 33 Group II) were matched from a total cohort of 106 patients with synchronous colorectal liver metastasis. The patients’ characteristics of both groups were similar. 62% were male and the mean age was 55.511 years. Blood loss and duration of surgery did not differ between simultaneous resections and staged resection (p¼0.63; p¼0.14, respectively). Perioperative complication rate were similar in both groups (P¼0.70). There was no mortality. The median number of in-hospital days during the course of treatment was 9 (4-23) days in Group I and 6 (3-17) days in Group II (p <0.001). There was no difference in 2 years disease free survival and overall survival were found between Group I and Group II ( 30% and 34%, p¼ 0.58; 67% and 62%, p¼0.86 respectively). CONCLUSIONS: Simultaneous liver resections result in similar short and long eterm outcomes as in patients undergoing sequential resections for synchronous colorectal cancer with comparable metastatic disease burden.

Item Type: Article (Meeting Abstract)
Additional Information: 8115/69804
Uncontrolled Keywords: synchronous colorectal liver metastases
Subjects: R Medicine > RD Surgery
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Medicine
Depositing User: Asst Prof Faisal Elagili
Date Deposited: 11 Apr 2019 11:25
Last Modified: 04 Jul 2023 11:28
URI: http://irep.iium.edu.my/id/eprint/69804

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