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In-vitro evaluation of porcupine bezoar extracts (PBE) as anti-cancer agent on HeLa cell line – A preliminary study

Azizulkarim, Azra Hazwanie and Abdul Jamil, Muhammad Mahadi and Adon, Mohamad Nazib and Abdul Wahab, Ridhwan and Tengku Ibrahim, Tengku Nadzlin and Hamdan, Salehhuddin and Baba, Sayang (2018) In-vitro evaluation of porcupine bezoar extracts (PBE) as anti-cancer agent on HeLa cell line – A preliminary study. In: 3rd International Sciences, Technology & Engineering Conference (ISTEC) 2018 - Material Chemistry, 18th April 2018, Penang, Malaysia.

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Abstract

Porcupine Bezoar Extract (PBE) has been previously described to possess diverse medicinal properties. In any case, its potential and ability as anti-cancer agent on HeLa cell line are still poorly studied and understood. Hence, in this research, Porcupine Bezoar Extract (PBE) aqueous extract was figure out for its potential as a safe anti-cancer agent. Initially, Porcupine Bezoar Extract (PBE) was infused with distilled water for 18 hours to get PBE aqueous solution in order to confirm the presence of bioactive agents as antioxidants. Later, PBE aqueous solution was subjected to HeLa cell line and was observed for 48 hours exposures with comparative to the untreated cell to evaluate its anticancer potential and ability. The data from this study propose the potential agents for improving human health, especially in the anti-cancer application.

Item Type: Conference or Workshop Item (Plenary Papers)
Additional Information: 5136/69660
Uncontrolled Keywords: In-vitro evaluation, porcupine bezoar extracts (PBE), anti-cancer agent on HeLa cell line
Subjects: R Medicine > RM Therapeutics. Pharmacology > RM300 Drugs and their action
Kulliyyahs/Centres/Divisions/Institutes: Kulliyyah of Allied Health Sciences
Kulliyyah of Allied Health Sciences > Department of Biomedical Science (Effective:1st July 2011)
Depositing User: Dr Ridhwan Abdul Wahab
Date Deposited: 18 Feb 2019 11:09
Last Modified: 15 Jul 2019 15:22
URI: http://irep.iium.edu.my/id/eprint/69660

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