Comparison of serum specific IgE with skin prick test in the diagnosis of allergy in Malaysia

Asha'ari, Zamzil Amin and Yusof, Suhaimi and Yusof, Rosnida Azura and Ismail, Rushdan and CYC, Maraina (2011) Comparison of serum specific IgE with skin prick test in the diagnosis of allergy in Malaysia. Medical Journal of Malaysia, 66 (3). pp. 202-206. ISSN 0300-5283

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Abstract

We compared a newer serum specific IgE (SSIgE) test with skin prick testing (SPT) in the diagnosis of allergy in Malaysia. Ninety newly diagnosed allergic patients were enrolled for both tests. Using SPT as a clinical gold standard,the sensitivity, specificity, positive, and negative predictive values (PPV, NPV) were calculated for SSIgE for each of the common allergens tested. The highest positive results for both SPT and SSIgE were for house dust mite and cat. Compared to SPT, SSIgE showed better sensitivity but poorer specificity, low PPV and good NPV in all the allergens tested. Significant positive correlation was seen between the diameter of wheal and flare of SPT and the SSIgE results.

Item Type:	Article (Journal)
Additional Information:	5556/6730
Uncontrolled Keywords:	Comparison, Skin prick test, Serum specific IgE, Allergy, Malaysia
Subjects:	R Medicine > RF Otorhinolaryngology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine > Department of Otolaryngology - Head and Neck Surgery
Depositing User:	Dr ZAMZIL AMIN ASHA'ARI
Date Deposited:	12 Dec 2011 12:34
Last Modified:	12 Dec 2011 12:34
URI:	http://irep.iium.edu.my/id/eprint/6730

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