Safety and efficacy of Viva QS® for smoking cessation among industrial workers in Kerteh and Kuantan, Malaysia

Mohamad Noor, Zaswiza and Md Aris, Mohd Aznan and Nik Mohamed, Mohamad Haniki and Draman, Samsul and Shaikh Rahman Bux, Siti Halimah Bux (2011) Safety and efficacy of Viva QS® for smoking cessation among industrial workers in Kerteh and Kuantan, Malaysia. International Medical Journal, 18 (3). pp. 188-193. ISSN 1341-2051

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Abstract

Objective: To evaluate the safety and efficacy of Viva QS®, an herbal medication consists of a combination of twelve herbs for smoking cessation in Malaysian adult smokers. Methods: A randomized, double-blind placebo-controlled study was conducted in the industrial factories in Kerteh and Kuantan, Malaysia. The subjects were recruited from those attended mobile smoking cessation programme (MSCP), agreed to sign written consent and fulfilled study criteria. Demographic and smoking history information, modified Fagerström test for nicotine dependence (FTND) score and carbon monoxide (CO) level were obtained at baseline. Follow-up were conducted by phone calls and/or face-to-face meetings at three time points. Viva QS® and placebo were supplied for 24 weeks. Results: One hundred and fifty-five subjects were randomized from 1st April 2008 to 26th October 2008 in the study. Biochemically verified 7-days point prevalence demonstrated Viva QS® significantly increased quit rate vs. placebo; 42.7% vs. 26.2% (p = 0.038) at week 4, 32.0% vs. 16.7% (p = 0.031) at week 12 and 30.7% vs. 13.9% (p = 0.015) at week 24. Adverse events reported were similar between groups. The most frequently reported adverse events were sore throat and dry mouth (36.6% and 17.8%, respectively for Viva QS® vs. 28.8% and 16.9% for placebo). Conclusions: Viva QS is safe and effective to aid smokers quit smoking in this population sample.

Item Type:	Article (Journal)
Additional Information:	5494/6714
Uncontrolled Keywords:	Safety, efficacy, herbal medication, smoking cessation
Subjects:	R Medicine > R Medicine (General) R Medicine > RS Pharmacy and materia medica
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine > Department of Community Health & Family Medicine Kulliyyah of Pharmacy > Department of Pharmacy Practice
Depositing User:	Prof Dr Mohd Aznan Md Aris
Date Deposited:	12 Dec 2011 11:25
Last Modified:	06 Feb 2015 11:38
URI:	http://irep.iium.edu.my/id/eprint/6714

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