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Saffron (Crocus sativus L.): as an antidepressant

Siddiqui, Mohammad Jamshed Ahmad and Saleh, Mohammed S M and Basharuddin, Siti Nur Balqis and Zamri, Siti Hajar and Mohd Najib, Mohd Hamizan and Che Ibrahim, Muhammad Zakirin and Mohd Noor, Nur Ain and Mazha, Hanin Nadiah and Mohd Hassan, Norazian and Khatib, Alfi (2018) Saffron (Crocus sativus L.): as an antidepressant. Journal of Pharmacy and Bioallied Sciences, 10 (4). pp. 1-8. ISSN 0975-7406 (In Press)

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Abstract

Saffron, Crocus sativus (Iridaceae), is a perennial herb, which earned its popularity as both medicine and spice. It is an inhabitant of different mountainous regions of Asia Minor to Greece, Western Asia, Egypt, and India. The benefits of saffron as an antidepressant are well-documented. Almost 150 volatile and nonvolatile compounds are obtained from the chemical analysis of this plant. Fewer than 50 constituents elucidated and identified so far showed phytochemical characteristics. The major bioactive compounds identified are safranal, crocin, and picrocrocin, which are responsible for its aroma as well as its bitter taste. This review is an attempt to encompass the methods of analysis and pharmacodynamic and pharmacokinetic properties of saffron followed by its efficacious and safe potential.

Item Type: Article (Review)
Additional Information: 6804/67054
Uncontrolled Keywords: Antidepressant, Crocus sativus, saffron, safranal
Subjects: Q Science > QD Chemistry
Kulliyyahs/Centres/Divisions/Institutes: Kulliyyah of Pharmacy
Kulliyyah of Pharmacy > Department of Pharmaceutical Chemistry
Depositing User: Dr M Jamshed Siddiqui
Date Deposited: 31 Oct 2018 15:38
Last Modified: 17 Dec 2018 12:00
URI: http://irep.iium.edu.my/id/eprint/67054

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