Different effect of hydroxyapatite granules in posterolateral spinal fusion in New Zealand white rabbit: a preliminary result

Buyong, Zunariah and Zakaria@Mohamad, Zamzuri and Zulkifly, Ahmad Hafiz and Khalid, Kamarul Ariffin (2009) Different effect of hydroxyapatite granules in posterolateral spinal fusion in New Zealand white rabbit: a preliminary result. In: Combined Meeting of 39th Malaysian Orthopaedic Association Annual Scientific Meeting & Annual Congress of The World Society for Endoscopic, Navigated & Minimal Invasive Spine Surgery, 21st-23rd May 2009, Kota Kinabalu, Sabah, Malaysia. (Unpublished)

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Abstract

The aim of this experimental study is to compare fusion status at lumbar intertransverse processes between implantation with hydroxyapatite (HA) granules alone, HA granules mixed with autologous platelet rich plasma (HA-PRP) and autograft. Twenty-four New Zealand white rabbits were used. The rabbits were randomized into two groups of 12 rabbits each based on the graft materials used. All the rabbits underwent single level bilateral lumbar fusion. One side of the animals was implanted with either HA alone or HA mixed with PRP. While the contra lateral sides were implanted with autograft, and served as the control. Four of the animals from each group were killed at 6, 12 and 16 weeks for undecalcified histological and radiological assessments. Preliminary results showed the control group with autograft healed with a good fusion mass. Interestingly, HA granules only group healed with better bone formation than HA-PRP.

Item Type:	Conference or Workshop Item (Speech/Talk)
Additional Information:	5178/66312
Uncontrolled Keywords:	hydroxyapatite, granules, NZW rabbit, spinal fusion, platelet rich plasma
Subjects:	Q Science > QH Natural history > QH301 Biology R Medicine > R Medicine (General) R Medicine > RD Surgery > RD701 Orthopedics
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine Kulliyyah of Medicine > Department of Basic Medical Kulliyyah of Medicine > Department of Department of Orthopaedics, Traumatology & Rehabilitation
Depositing User:	Assoc. Prof. Dr. Kamarul Ariffin Khalid
Date Deposited:	08 Oct 2018 10:26
Last Modified:	08 Oct 2018 10:26
URI:	http://irep.iium.edu.my/id/eprint/66312

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