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Antifungal effects of Eurycoma longifolia jack (Tongkat Ali) root extract against oral Candida albicans

Faisal, Ghasak Ghazi and Arzmi, Mohd Hafiz and Alloha, Irani and Aziz, Nurul ‘Ain Liyana and Abllah, Zurainie (2018) Antifungal effects of Eurycoma longifolia jack (Tongkat Ali) root extract against oral Candida albicans. In: International Conference on Oral Immunology and Oral Microbiology (ICOIOM 2018), 14th-15th Aug. 2018, Kuala Lumpur.

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Abstract

Abstract: Eurycoma longifolia jack (E.L) is a herbal medicinal plant of South-East Asian origin, popularly recognized as ‘Tongkat Ali.’ The plant roots have been scientifically proven to have many biological effects.This study was done to determine the antifungal activities of E.L. root extract against Candida albicans. E.L root was extracted using soxhlet method. Disc diffusion assay was conducted using extract concentration of 200mg/ml. Nystatin was used as positive control. Minimum Inhibitory Concentration (MIC) was done to determine the lowest inhibitory concentration of the extract on the microorganism. E.L extract inhibited the growth of Candida albicans at a concentration of 200mg/ml with a zone of inhibition of 16.0 ± 3.0mm . The MIC of E.L extract against Candida albicans was 25mg/ml. The results from this study revealed the potential use of Eurycoma longifolia jack as an antifungal agent which can be used to produce new oral care products.

Item Type: Conference or Workshop Item (Poster)
Additional Information: 6388/66092
Uncontrolled Keywords: Eurycoma longifolia jack, root extract, Candida albicans
Subjects: R Medicine > RK Dentistry > RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works
Kulliyyahs/Centres/Divisions/Institutes: Kulliyyah of Dentistry
Depositing User: Assoc.Prof Ghasak Ghazi Al-Atrakchi
Date Deposited: 01 Oct 2018 12:45
Last Modified: 01 Oct 2018 12:45
URI: http://irep.iium.edu.my/id/eprint/66092

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