Primary Hodgkin’s lymphoma with chest wall ulceration and hypereosinophilia: a rare presentation and diagnostic dilemma

Wan Ali, Wan Ahmad Syahril Rozli and Tumian, Nur Rafeah (2018) Primary Hodgkin’s lymphoma with chest wall ulceration and hypereosinophilia: a rare presentation and diagnostic dilemma. Indian Journal of Case Reports, 14 (2 (Mar-Apr)). pp. 121-123. ISSN 2454-129X E-ISSN 2454-1203

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Abstract

Hodgkin’s lymphoma (HL) with cutaneous manifestation is a rare condition which usually occurred late in the course of the disease. Due to its rare presentation, misdiagnoses are common. We report a 26-year-old Chinese gentleman who presented with painless and large anterior chest wall ulceration. Computed tomography scan showed sternal mass and erosion, with skin and anterior mediastinal extension. The second histopathologic examination (with immunohistochemistry) of the skin biopsy showed HL with mixed cellularity pattern. However, there was a marked dominance of eosinophils in both the peripheral blood and the tissue samples. This was a very unusual presentation of extranodal HL with ulceration and pronounced hypereosinophilia. The diagnosis was only made after the second biopsy because of the rare occurrence.

Item Type:	Article (Journal)
Additional Information:	5229/64422
Uncontrolled Keywords:	Hypereosinophilia, Primary Hodgkin’s lymphoma, Sternal erosion
Subjects:	R Medicine > R Medicine (General)
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine > Department of Internal Medicine
Depositing User:	Dr. Wan Ahmad Syahril Rozli Wan Ali
Date Deposited:	10 Jul 2018 10:05
Last Modified:	03 Jan 2019 10:52
URI:	http://irep.iium.edu.my/id/eprint/64422

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