Toxicity profiles between strains of Alexandrium Tamiyavanichii

Muhamad Bunnori, Noraslinda and Mohammad Noor, Normawaty and Abd Hamid, Shafida and Hamdan, Nurul Ashima and Abu Hassan, Muhamad Shafiq (2018) Toxicity profiles between strains of Alexandrium Tamiyavanichii. In: ISERD- 325TH. INTERNATIONAL CONFERENCE ON ENVIRONMENT AND NATURAL SCIENCE (ICENS, 8-9 February 2018, Osaka, Japan. (Unpublished)

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Abstract

Phycotoxins are byproducts of toxic microalga that capable of causing severity on humans upon consuming contaminated seafood. The amount of toxins released by microalgae varies according to species as some of the microalgae synthesize toxins within small number of cells while others required a blooming event for the toxins to be detected. It is also possible for the toxicity of one species being gradually decreases throughout years in culture. Alexandrium tamiyavanichii has been reported to cause toxicity in seafood products that subject to hospitalized cases in Malaysia. Genus Alexandriumhas been known for its stability in producing toxins yet no total loss of toxicity has been recorded. Two cultures of A. tamiyavanichii have been tested for its toxicity using high-performance liquid hromatography (HPLC) with GTX standards as reference. Strains isolated from Kuantan Port during recent cases of paralytic shellfish poisoning (PSP) outbreak showed extremely high in total toxin content (3.07 nmol.cell-1) while the clonal culture of A. tamiyavanichii established from Sebatu Malacca exhibited very low level of toxicity (1.167 fmol.cell-1). There are many factors influencing toxicity properties of A. tamiyavanichii with highlights in nutrients deprivation and adaptation as well as bacterial influences for the aged culture.

Item Type:	Conference or Workshop Item (Speech/Talk)
Additional Information:	6604/63373
Uncontrolled Keywords:	Alexandrium spp., toxin profiling, post-column HPLC, gonyautoxins
Subjects:	Q Science > QL Zoology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Science > Department of Biotechnology
Depositing User:	Dr. Noraslinda Muhamad Bunnori
Date Deposited:	26 Apr 2018 16:47
Last Modified:	26 Apr 2018 16:47
URI:	http://irep.iium.edu.my/id/eprint/63373

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