Persistence patterns of opioid use over three follow-up years: the difference between non-cancer and cancer pain

Abdullah Sani, Asween Rowena and Zin, Che Suraya and Mohamed, Abdul Hadi and Izat, Munira and Ng, Kim Swan (2018) Persistence patterns of opioid use over three follow-up years: the difference between non-cancer and cancer pain. In: 6th Biennial Scientific Meeting Malaysian Association for the Study of Pain 2018, 17th-18th March 2018, Putrajaya, Malaysia.

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Abstract

Persistence Patterns Of Opioid Use Over Three Follow-Up Years: The Difference Between Non-cancer And Cancer Pain Asween Rowena Sani1, Che Suraya Zin1, Abdul Hadi Mohamed1, Munira Izat2, Tan Hung Ling2 and Ng Kim Swan3 1International Islamic University Malaysia, Kuantan, Pahang, Malaysia. 2Hospital Kuala Lumpur, Kuala Lumpur, Malaysia. 3Hospital Selayang, Selangor, Malaysia. Background: This study examined the persistence patterns of opioid use in patients with non-cancer and cancer pain over three follow-up years. Methods: All prescriptions for opioids (buprenorphine, dihydrocodeine, fentanyl, oxycodone, morphine) issued by the outpatient tertiary hospital settings between 2013 and 2015 were examined. Wide definition of persistence refers to patients prescribed >0.7DDD or >16.7mg morphine equivalents (MME) per day for at least 3 quarters of a year. Intermediate persistence refers to patients prescribed >1 DDD or 12.3 MME per day in a year, and strict persistence refers to patients prescribed >2 DDD or 49.3 MME per day in a year. Patients who did not meet any of the definitions were categorized as non-persistent. The number of patients in each definition at the end of a 3-year follow-up period were calculated. Analyses were performed using Stata 13. Results: Non-persistent opioid users were predominant in both non-cancer (86%) and cancer (94%) groups. Persistent opioid users in the wide, intermediate, and strict definitions at the end of follow up period were 19% (n=4/21) ,43% (n=3/7), and 25% (n=1/4) vs. 6% (n=2/31), 0% (n=0/3), and 17% (n=1/6) in the non-cancer vs. cancer groups respectively. Conclusion: Non-cancer pain patients in the intermediate and cancer pain in the strict definitions were most likely to continue opioid treatment over a 3-year period. Future work to determine factors related to differential in persistence patterns of opioid use particularly in non-cancer pain patients. Acknowledgement: CSZ was supported by research grants from the Ministry of Education Malaysia Fundamental Research Grant Scheme-FRGS 15-195-0436).

Item Type:	Conference or Workshop Item (Speech/Talk)
Additional Information:	4127/63286
Uncontrolled Keywords:	opioid use, non-cancer, cancer pain
Subjects:	R Medicine > RS Pharmacy and materia medica
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Pharmacy > Department of Pharmacy Practice
Depositing User:	Prof Dr Che Suraya Mohd Zin
Date Deposited:	25 Apr 2018 10:20
Last Modified:	26 Jun 2018 15:35
URI:	http://irep.iium.edu.my/id/eprint/63286

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