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Formulation and characterization of cosmetic cream incorporating piper Betle Linn. extract

Hanif, Nadzira and Doolaanea, Abd Almonem and Ab. Hadi, Hazrina (2017) Formulation and characterization of cosmetic cream incorporating piper Betle Linn. extract. In: Malaysia Pharmaceutical Society Conference 2017, 3-5 November, 2017, Penang, Malaysia.

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INTRODUCTION: Piper betle Linn. is an evergreen and perennial plant with glossy heart-shaped leaves which contains various biologically active compounds. Hydroxychavicol is a phenolic compound found in Piper betle leaves which exhibits many potential biological activities such as antimicrobial, antioxidant, anti-inflammatory and anti-tyrosinase.OBJECTIVES: The study aimed to formulate cosmetic cream incorporating Piper betle extract and to characterize the developed cream.METHODS: The cosmetic cream containing 0.02% Piper betle extract was developed by incorporating three phase ingredients include aqueous phase (75.2%), oil phase (20.8%) and cooling phase (4.0%). O/W emulsion was prepared by adding aqueous phase into oil phase through a combination process of heating up to 75℃ and homogenization at 3500 rpm. The cream formulation was characterized for organoleptic properties, pH, particle size, zeta potential, rheological behaviour and microbial limit test.RESULTS: For organoleptic properties, the cream has an off white color, pleasant odour, smooth texture and no phase separation. The cream formulation has a pH value of 5.39 ± 0.03 which was near to skin pH (4.5-5.5), smaller particle size of 3.73 ± 0.01 µm and polydispersity index of 0.56 ± 0.11, negatively zeta potential of -57.53 ± 1.47 mV and exhibited non-Newtonian behavior in which viscosity decreases when shear rate increases. The cream has no growth of viable microorganisms, yeasts and fungi.CONCLUSION: Based on physical characterization, the cream containing 0.02% Piper betle extract is regarded as a stable formulation with acceptable organoleptic properties.Keywords: Characterization, cream, formulation, oil in water emulsion, Piper betle Linn.

Item Type: Conference or Workshop Item (Poster)
Additional Information: 5589/61757
Uncontrolled Keywords: Formulation and characterization; Cosmetic cream; Piper Betle Linn. extract
Subjects: R Medicine > RS Pharmacy and materia medica
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Pharmacy > Department of Pharmaceutical Technology
Depositing User: Dr Hazrina Ab Hadi
Date Deposited: 20 Feb 2018 12:11
Last Modified: 29 Jun 2018 11:27
URI: http://irep.iium.edu.my/id/eprint/61757

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