Isolation and identification of flavonoids from Tetracera indica Merr. (Dilleniaceae) leaves

Ahmed, Qamar Uddin and Alhassan, MA and Hasan, Md. Mahmudul (Stu) and Khatib, Alfi and Sarian, Murni Nazira and Latip, Jalifah (2016) Isolation and identification of flavonoids from Tetracera indica Merr. (Dilleniaceae) leaves. In: 2nd International Conference on Industrial Pharmacy (ICIP 2016), 15th-16th Aug. 2016, Kuantan, Pahang. (Unpublished)

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Abstract

Leaves of Tetracera indica are used in traditional medicine for the treatment of diabetes mellitus in Malaysia. This study was aimed at investigating the phytochemical constituents present in T. indica leaves which may be responsible for the antidiabetic effect of the plant’s leaves. Crude methanolic extract from the leaves of T. indica was separated and purified by column chromatography of silica gel, ODS and sephadex LH-20. The structures of the isolated compounds were identified and elucidated by UV, 1H-NMR, 13C-NMR and MS spectroscopic techniques. Four flavonoids were isolated from the leaves of T. indica, and these compounds were identified as follows: 5,7-dihydroxy-8-methoxyflavone (wogonin), 5,7,8-trihydroxyflavone (norwogonin), quercetin and 5-Hydroxy-7-methoxyflavone (tectochrysin). The three compounds i.e. norwogonin, quercetin and tectochrysin are being reported for the first time from T. indica leaves. Keywords: Tetracera indica, flavonoids, diabetes mellitus

Item Type:	Conference or Workshop Item (Poster)
Additional Information:	4921/61096
Uncontrolled Keywords:	Isolation and identificatio; flavonoids; Tetracera indica Merr; Dilleniaceae leaves
Subjects:	Q Science > Q Science (General) Q Science > QD Chemistry
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Pharmacy Kulliyyah of Pharmacy > Department of Pharmaceutical Chemistry
Depositing User:	Dr Qamar Uddin Ahmed
Date Deposited:	25 Jan 2018 12:01
Last Modified:	04 Jan 2019 11:06
URI:	http://irep.iium.edu.my/id/eprint/61096

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