Risk factors for anti tuberculous drugs induced hepatitis: a prospective survey from a chest clinic in a general hospital

Abdul Rani, Mohammed Fauzi and Rathor, Mohammad Yousuf and Mohd Shah, Azarisman Shah and Satwi, Sapari (2004) Risk factors for anti tuberculous drugs induced hepatitis: a prospective survey from a chest clinic in a general hospital. Medical Journal of Malaysia, 59 (1). pp. 72-77. ISSN 0300-5283

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Abstract

A prospective survey on 14 consecutive cases with tuberculous drug induced hepatitis was done at our chest clinic in a state general hospital over a period of 15 months. There were 30 controls chosen randomly from the chest clinic register. The cases had lower mean body mass index (P<0.008), serum albumin (P<0.005) and higher serum globulin (P<0.04). Serum liver transaminases and total bilirubin rose significantly during the acute episode of drug induced hepatitis. Among the risk factors studied, only chronic hepatitis B carrier status was found to be more prevalent among the cases. There was one death (7.1%) over the whole study period.

Item Type:	Article (Journal)
Additional Information:	3204/6035
Uncontrolled Keywords:	Prospective survey, Tuberculosis drug, Hepatotoxicity, Risk factors
Subjects:	R Medicine > R Medicine (General)
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine > Department of Internal Medicine
Depositing User:	Prof Dr Mohammed Fauzi Abdul Rani
Date Deposited:	31 Oct 2011 10:41
Last Modified:	10 Jul 2014 12:40
URI:	http://irep.iium.edu.my/id/eprint/6035

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