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Invasive rhinocerebral mucormycosis with orbital extension in poorly- controlled diabetes mellitus

Hasmoni, Mohamed Hadzri and Mohd Shah, Azarisman Shah and Abdul Rani, Mohammed Fauzi and Abdullah, Kahairi (2009) Invasive rhinocerebral mucormycosis with orbital extension in poorly- controlled diabetes mellitus. Singapore Medical Journal (SMJ), 50 (3). e 107-e 109. ISSN 0037-5675

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Abstract

Rhinocerebral mucormycosis is an invasive fungal sinusitis with a high mortality rate, especially in immunocompromised patients. A 70-year-old woman, with uncontrolled type 2 diabetes mellitus, presented with a one-month history of non-specific headaches associated with progressive swelling of her left eye. Computed tomography of the brain and orbits showed the extensive involvement of bilateral intranasal sinuses, orbits, extraocular muscle and soft tissues. The diagnosis of invasive mucormycosis was confirmed from a tissue biopsy taken from the internasal septum. Despite the extensive mucormycosis invasion, she was successfully treated with intranasal and systemic amphotericin B and minimal adjunctive intranasal sphenoidotomy.

Item Type: Article (Journal)
Additional Information: 1766/5864
Uncontrolled Keywords: amphotericin B, diabetes mellitus, fungal sinusitis, proptosis, rhinocerebral mucormycosis
Subjects: R Medicine > R Medicine (General)
Kulliyyahs/Centres/Divisions/Institutes: Kulliyyah of Medicine > Department of Internal Medicine
Depositing User: Prof Dr Mohammed Fauzi Abdul Rani
Date Deposited: 01 Nov 2011 09:17
Last Modified: 12 May 2012 14:33
URI: http://irep.iium.edu.my/id/eprint/5864

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