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Nanomaterial biocompatibility and antimicrobial effects on Escherichia coli

Sanober, Fahmi and Ahmad, Siti Khadijah and Wan Salim, Wan Wardatul Amani (2017) Nanomaterial biocompatibility and antimicrobial effects on Escherichia coli. Asia-Pacific Journal of Molecular Biology and Biotechnology, 25 (1). pp. 1-4. ISSN 0128-7451

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We studied the effects of cultivating E. coli with nanomaterials involved in biosensor development. E. coli were cultured separately with each of these nanomaterials in Luria-Bertani broth medium. Bacterial growth curves were plotted by measuring optical density over a period of 12 hours, after which time bacterial cell dry weight was measured. After 12 hours of incubation, optical density was 0.588, 0.983, and 0.633 and cell dry weight was 4.6 × 10-3 g/ml, 4.9 × 10-3 g/ml, and 4.1 × 10-3 g/ml for bacteria cultivated in the presence of CNTs, AgNPs, and AuNPs respectively, suggesting that these nanomaterials have bactericidal or antimicrobial properties. On the other hand, graphene oxide (GO) does not have intrinsic bactericidal, cytotoxic, and/or antibacterial properties and greatly enhances bacterial growth. These findings advance our knowledge concerning the properties of nanomaterials and can guide the selection of appropriate nanomaterials for the fabrication of the transducer layer of a biosensor.

Item Type: Article (Journal)
Additional Information: 7116/58593
Uncontrolled Keywords: Escherichia coli, biosensors, nanomaterials, antimicrobial, biocompatibility
Subjects: Q Science > Q Science (General)
Q Science > QR Microbiology
T Technology > T Technology (General)
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Engineering > Department of Biotechnology Engineering
Depositing User: Dr Wan Wardatul Amani Wan Salim
Date Deposited: 02 Oct 2017 10:33
Last Modified: 01 Feb 2018 01:30
URI: http://irep.iium.edu.my/id/eprint/58593

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