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A lignan with glucose uptake activity in 3T3-L1 adipocytes from the stem bark of Knema patentinervia

Bakhtiar, M. Taher and Mohamed Amiroudine, Mohamed Zaffar Ali and Md Jaffri, Juliana and Amri, Mohamad Shahreen and Darnis, Deny Susanti and Abd Hamid, Shafida and Rezali, Mohd Fazlin and Mahmood Hasan, Choudhury and W Read, Roger and Ahmed, Qamar Uddin and Ahmad, Farediah (2017) A lignan with glucose uptake activity in 3T3-L1 adipocytes from the stem bark of Knema patentinervia. Pakistan Journal of Pharmaceutical Science, 30 (4). pp. 1335-1339. ISSN 1011-601X

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Abstract

A new naturally occurring dibenzylbutyrolactone lignan named isocubebinic ether has been isolated from Knema patentinervia. The structure was established by spectroscopic methods, which include Ultraviolet, Infrared, Nuclear Magnetic Resonance and Mass Spectrometry. The compound showed activity in the stimulation of glucose uptake by 3T3-L1 adipocytes.

Item Type: Article (Journal)
Additional Information: 5209/57378
Uncontrolled Keywords: Knema patentinervia, lignan, glucose uptake, 3T3-L1 adipocytes.
Subjects: R Medicine > RS Pharmacy and materia medica
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Pharmacy > Department of Pharmaceutical Chemistry
Kulliyyah of Pharmacy > Department of Pharmaceutical Technology
Kulliyyah of Science > Department of Chemistry
Depositing User: Dr Muhammad Taher
Date Deposited: 05 Jul 2017 09:21
Last Modified: 27 Mar 2018 16:58
URI: http://irep.iium.edu.my/id/eprint/57378

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