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The effect of pasteurization on trace elements in donor breast milk

Mohd Taufek, Nor Hidayah and Cartwright, David William and Davies, Mark W. and Hewavitharana, Amitha K and Koorts, Pieter J. and McConachy, Helen and Shaw, Paul Nicholas and Sumner, Ronald and Whitfield, Karen M. (2016) The effect of pasteurization on trace elements in donor breast milk. Journal of Perinatology, 36 (10). pp. 897-900. ISSN 0743-8346

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Abstract

OBJECTIVE: Premature infants often receive pasteurized donor human milk when mothers are unable to provide their own milk. This study aims to establish the effect of the pasteurization process on a range of trace elements in donor milk. STUDY DESIGN: Breast milk was collected from 16 mothers donating to the milk bank at the Royal Brisbane and Women’s Hospital. Samples were divided into pre- and post-pasteurization aliquots and were Holder pasteurized. Inductively coupled plasma mass spectrometry was used to analyze the trace elements zinc (Zn), copper (Cu), selenium (Se), manganese (Mn), iodine (I), iron (Fe), molybdenum (Mo) and bromine (Br). Differences in trace elements pre- and post-pasteurization were analyzed. RESULTS: No significant differences were found between the trace elements tested pre- and post-pasteurization, except for Fe(P<0.05). The median (interquartile range, 25 to 75%; μg l− 1) of trace elements for pre- and post- pasteurization aliquots were—Zn: 1639 (888–4508), 1743 (878–4143), Cu: 360 (258–571), 367 (253–531), Se: 12.34 (11.73–17.60), 12.62 (11.94–16.64), Mn:(1.48 (1.01–1.75), 1.49 (1.11–1.75), I (153 (94–189), 158 (93–183), Fe (211 (171–277), 194 (153–253), Mo (1.46 (0.37–2.99), 1.42(0.29–3.73) and Br (1066 (834–1443), 989 (902–1396).CONCLUSIONS: Pasteurization had minimal effect on several trace elements in donor breast milk but high levels of inter-donor variability of trace elements were observed. The observed decrease in the iron content of pasteurized donor milk is, however, unlikely to be clinically relevant.

Item Type: Article (Journal)
Additional Information: 6410/56681
Uncontrolled Keywords: EMTREE drug terms: bromine; copper; iodine; iron; manganese; molybdenum; selenium; trace element; zinc EMTREE medical terms: adult; Article; breast milk; concentration (parameters); controlled study; donor; female; human; mass spectrometry; milk bank; milk level; pasteurization
Subjects: R Medicine > RJ Pediatrics
Kulliyyahs/Centres/Divisions/Institutes: Kulliyyah of Pharmacy > Department of Pharmacy Practice
Depositing User: Nor Hidayah Mohd Taufek
Date Deposited: 25 Apr 2017 16:45
Last Modified: 06 Sep 2017 00:45
URI: http://irep.iium.edu.my/id/eprint/56681

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