Between the bioactive extracts of edible mushrooms and pharmacologically important nanoparticles: Need for the investigation of a synergistic combination - A mini review

Ishmael, Ukaegbu Chinonso and Rashid, Shah Samiur and Khan Chowdhury, Ahmed Jalal and Sarkar, Shaheen and Hamid, Hazrulrizawati A. and Azmi, Nina Suhaity (2017) Between the bioactive extracts of edible mushrooms and pharmacologically important nanoparticles: Need for the investigation of a synergistic combination - A mini review. Asian Journal of Pharmaceutical and Clinical Research, 10 (3). pp. 13-24. ISSN 0974-2441 E-ISSN 2455-3891

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Abstract

The pharmacological potential of bioactive compounds extracted from mushrooms has been studied to a reasonable level. In the same vein, the bioactivity of nanoparticles has also been investigated and reported to be of potential pharmacological benefit. No doubt, there is a reasonable amount of claims regarding the vast activity of the mushroom extracts and nanoparticles on the tested cell lines and microorganisms. In this paper, a review of the recent application of bioactive compounds extracted from two edible mushrooms (Coprinus comatus and Lactarius deliciosus), as well as some of the recently reported studies on some nanoparticles of pharmacological potentials, was carried out. In order to check for synergy in the bioactivity of the mushroom extracts when co-administered with nanoparticles, an investigation on the synergistic application of the materials through the encapsulation of the bioactive extracts from the mushroom onto the nanoparticle was proposed. The supposed synergy in the activity of the extract-nanoparticle complex could hold the key to improved activity of nutraceuticals against resistant microorganisms and tumor cells.

Item Type:	Article (Review)
Additional Information:	3575/56553
Uncontrolled Keywords:	Coprinus comatus, Lactarius deliciosus, Nanoparticles, Synergy, Bioactive extracts
Subjects:	R Medicine > RS Pharmacy and materia medica
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Science > Institute of Oceanography and Maritime Studies
Depositing User:	Professor Ahmed Jalal Khan Chowdhury
Date Deposited:	19 Jun 2017 15:15
Last Modified:	05 Apr 2018 13:37
URI:	http://irep.iium.edu.my/id/eprint/56553

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