Post herpetic neuralgia after acyclovir treatment

Mohamed, Abdul Hadi and Awang, Mohd Shukrimi and Abdullah, Nor Zamzila and Mat Nor, Mohd Basri (2016) Post herpetic neuralgia after acyclovir treatment. In: Medical Research Symposium & Pacific Partnership in conjunction with Kuantan Research Day 2016, 3rd-5th August 2016, Kuantan, Pahang.

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Abstract

Post Herpetic Neuralgia (PHN) is often diagnosed when pain persists in a dermatomal pattern weeks after the herpes zoster vesicular eruption has healed. There is a definite tendency for PHN to improve with time. There is no way of predicting who will recover. However, some reported that as many as 40% of patients with PHN will continue to have long-term problems because of incomplete or no pain despite the best treatments given. This retrospective series discussed the outcome of treatment of 3 patients with PHN, using acyclovir, Gabapentin and analgesics. Patients were treated by a single pain specialist in a conventional community pain practice. Therapies were given twice-monthly for 1-2 months, then less frequently until pain relief was optimized. Patients received a median of 7 treatments (range 4 - 11). Median baseline allodynia levels were reduced from 9 /10 (range 8 to 10) to 0/10 (range 0 to 6), intermittent shooting pain from 9/10 (range 8 to 10) to 0/10 (range 0 to 6). 1 of 3 patients (30%) was able to be weaned off pain medications. These data showed that there is variation in the response to treatment in patients suffering from PHN. The response ranged from a complete cure to unresponsive at all to the treatment given. There is no way of predicting who will fully recover.

Item Type:	Conference or Workshop Item (Plenary Papers)
Additional Information:	3439/55190
Uncontrolled Keywords:	herpes zoster, acyclovir, post herpetic neuralgia, gabapentin
Subjects:	R Medicine > RM Therapeutics. Pharmacology > RM695 Physical medicine. Physical therapy
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine > Department of Anaesthesiology & Intensive Care
Depositing User:	Dr Nor Zamzila Abdullah
Date Deposited:	27 Feb 2017 10:44
Last Modified:	15 Jul 2020 10:49
URI:	http://irep.iium.edu.my/id/eprint/55190

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