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Performance of STAR virtual trials for diabetic and non-diabetic in HTAA Intensive Care Unit

Jamaludin, Ummu Kulthum and Dzaharudin, Fatimah and Humaidi, M. Luqman and W.M. Zulkifly, W Zuhriraihan and Md Ralib, Azrina and Mat Nor, Mohd Basri and A Razak, Normy and Suhaimi, Fatanah M. and Pretty, Christopher G. (2016) Performance of STAR virtual trials for diabetic and non-diabetic in HTAA Intensive Care Unit. In: 2016 IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES), 4th-8th December 2016, Kuala Lumpur.

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Critically ill patients are commonly linked to stress-induced hyperglycaemia which relates to insulin resistance and the risk of per-diagnosed with diabetes and other metabolic illnesses. Thus, it is essential to choose the best practice of blood glucose management in order to reduce morbidity and mortality rates in intensive care unit. This study is focusing on clinical data of 210 critically ill patients in Hospital Tengku Ampuan Afzan (HTAA), Kuantan who underwent Intensive Insulin Therapy which utilized a sliding scale method. Patients were identified in two main groups of diabetic (123) and non-diabetic (87) where stochastic model is generated to observe 90% confidence interval of insulin sensitivity. Blood glucose levels comparison between these two cohorts is conducted to observe the percentage of blood glucose levels within targeted band of 4.4 – 10.0 mmol/L. It is found that 82% of BG levels are within targated band for non-diabetes cohort under stochastic targeted (STAR) glycaemic control protocol. However, only 59.6% and 70.6% BG levels are within targeted band for diabetes cohort for insulin infusion therapy used in HTAA and STAR protocols. Thus, further investigation on blood glucose control protocol for diabetes patients is required to increase the reliability and efficacy of current practice despite of patient safety.

Item Type: Conference or Workshop Item (Plenary Papers)
Additional Information: 3934/54922
Uncontrolled Keywords: glycaemic protocol; virtual trial; blood glucose; insulin sensitivity; intensive care; diabetes
Subjects: R Medicine > R Medicine (General)
R Medicine > RA Public aspects of medicine > RA644.3 Chronic and Noninfectious Diseases and Public Health
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Medicine
Kulliyyah of Medicine > Department of Anaesthesiology & Intensive Care
Depositing User: Prof Azrina Md Ralib
Date Deposited: 21 Feb 2017 14:51
Last Modified: 15 Jul 2020 10:55
URI: http://irep.iium.edu.my/id/eprint/54922

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