Implementation of a prototype glomerular filtration rate application to monitor creatinine kinetic dynamics in critically ill patients

Dzaharudin, Fatimah and Md Ralib, Azrina and Mat Nor, Mohd Basri and Jamaludin, Ummu Kulthum (2016) Implementation of a prototype glomerular filtration rate application to monitor creatinine kinetic dynamics in critically ill patients. In: 2016 IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES), 4th-8th December 2016, Kuala Lumpur.

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Abstract

It has always been desirable for clinicians to ascertain whether glomerular filtration rate has recovered or still depressed at the bedside as increase in serum creatinine often indicates acute kidney injury to a clinician. In recent years, several clinical studies have developed mathematical models to simulate the creatinine response to changes in glomerular filtration rate which includes the estimated glomerular filtration rate Chronic Kidney Disease Epidemiology Collaboration, the Chen-kinetic estimated GFR model and the modified Chen-Pianta-Endre-Pickering-Bukley-Pecke kinetic estimated GFR model. Another study also showed that the ratio of creatinine excretion rates to creatinine production rates may predict changes in plasma concentration. The aim of this study is to allow clinicians to gauge the performance of glomerular filtration rate estimation using the aforementioned equations and models to predict worsening of renal function, indicated by a low kinetic estimated glomerular filtration rate or creatinine production rates less than unity, or recovery of kidney function, indicated by high kinetic estimated glomerular filtration rate. In order to achieve this a mobile software is developed to aid data collection and calculation for the clinical study based on the aforementioned models. This paper summarises the implementation details of the native application development and presents the graphical user interface of the system in practice.

Item Type:	Conference or Workshop Item (Plenary Papers)
Additional Information:	3934/54920
Uncontrolled Keywords:	prototype glomerular filtration, creatinine kinetic dynamics,
Subjects:	R Medicine > R Medicine (General)
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine > Department of Anaesthesiology & Intensive Care
Depositing User:	Prof Azrina Md Ralib
Date Deposited:	21 Feb 2017 12:30
Last Modified:	15 Jul 2020 10:53
URI:	http://irep.iium.edu.my/id/eprint/54920

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