Prevalence of elevated aldosterone renin ratio in three main states of Peninsular Malaysia

Saud Gany, Siti Liyana and Shahar, Mohammad Arif and Sukor, Norlela and Omar, Ahmad Marzuki and A Wahab, Norasyikin and MY, Yusniza and Azizan, Elena and Chong, Kuck Meng and Md Zain, Rabizah and Long, Kha Ching and Mohd Razali, Amyliation and Zainuddin, Noradilah and Mat, Nurul Hani and Mender, Fadlin and Muhair, Musilawati and Othman, Hanita and Yusof, Siti Fatehah and Rahmat, Norhisham and Saufi, Ahmad and Bador, Khalidah Mazlan and Kamaruddin, Nor Azmi (2016) Prevalence of elevated aldosterone renin ratio in three main states of Peninsular Malaysia. In: 7th MEMS Annual Congress, 19-22 May 2016, Kuala Lumpur.

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Abstract

Objective: The objective of this study was to determine the prevalence of increased Aldosterone Renin Ratio (ARR) in parts of Selangor, Perak and Pahang. Methods: This was a cross sectional study involving subjects in Selangor, Perak and Pahang. The World Health Survey Kish tables were used to select eligible subjects (≥18 years old) from each household. Their social demography, past medical history, anthropometric measurement and blood pressure were recorded. Blood were withdrawn for Aldosterone (ALD), Plasma Renin Activity (PRA), Creatinine (creat) and potassium (K). Raised ARR is defined as aldosterone/renin ratio of more than 20. Results: A total of 1073 subjects (age 50 +/- 16.4). One hundred and nineteen (11.1%) subjects showed an ARR =/> 20. Forty nine (41.2%) out of the elevated ARR =/> 20 were hypertensive, 11 of which were not taking any anti-hypertensive drugs and 54 subjects (45.4%) were normotensive. Only 7 (5.9%) of them were hypokalemic, one of them being hypertensive. The main clinical characteristics of subjects with raised ARR are shown in Table 1. Conclusion: The prevalence of raised ARR in Rural Selangor was 11.1%, and only 5.9% of them were hypokalemic.

Item Type:	Conference or Workshop Item (Speech/Talk)
Additional Information:	5471/52077
Uncontrolled Keywords:	elevated aldosterone renin ratio, Peninsular Malaysia
Subjects:	R Medicine > RC Internal medicine
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine > Department of Internal Medicine
Depositing User:	Dr Mohammad Arif Shahar
Date Deposited:	06 Oct 2016 11:23
Last Modified:	17 Jan 2017 15:29
URI:	http://irep.iium.edu.my/id/eprint/52077

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