Cohort profile: The Malaysian Cohort (TMC) project: a prospective study of non-communicable diseases in a multi-ethnic population

Jamal, Rahman and Syed Zakaria, Syed Zulkifli and Kamaruddin, Mohd Arman and Abd Jalal, Nazihah and Ismail, Norliza and Mohd Kamil, Norkhamiwati and Abdullah, Noraidatulakma and Baharudin, Norhafizah and Hussin, Noor Hamidah and Othman, Hanita and Mahadi, Nor Muhammad and Mamat,, Nik Mazlan (2015) Cohort profile: The Malaysian Cohort (TMC) project: a prospective study of non-communicable diseases in a multi-ethnic population. International Journal of Epidemiology, 44 (2). pp. 423-431. ISSN 0300-5771 E-ISSN 1464-3685

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Abstract

The Malaysian Cohort study was initiated in 2005 by the Malaysian government. The topdown approach to this population-based cohort study ensured the allocation of sufficient funding for the project which aimed to recruit 100 000 individuals aged 35–70 years. Participants were recruited from rural and urban areas as well as from various socioeconomic groups. The main objectives of the study were to identify risk factors, to study gene-environment interaction and to discover biomarkers for the early detection of cancers and other diseases. At recruitment, a questionnaire-based interview was conducted, biophysical measurements were performed and biospecimens were collected, processed and stored. Baseline investigations included fasting blood sugar, fasting lipid profile, renal profile and full blood count. From April 2006 to the end of September 2012 we recruited a total of 106 527participants. The baseline prevalence data showed 16.6% participants with diabetes, 46.5% with hypertension, 44.9% with hypercholesterolaemia and 17.7% with obesity. The follow-up phase commenced in June 2013. This is the most comprehensive and biggest cohort study in Malaysia, and has become a valuable resource for epidemiological and biological research. For information on collaboration and also data access, investigators can contact the project leader at (rahmanj@ppukm.ukm.edu.my).

Item Type:	Article (Journal)
Additional Information:	4617/51565
Uncontrolled Keywords:	biomarkers, non-communicable diseases, Malaysian Cohort study
Subjects:	R Medicine > R Medicine (General) R Medicine > RA Public aspects of medicine
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Allied Health Sciences > Department of Nutrition Sciences
Depositing User:	Dr Nik Mazlan Mamat
Date Deposited:	15 Aug 2016 11:21
Last Modified:	15 Aug 2016 11:21
URI:	http://irep.iium.edu.my/id/eprint/51565

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