The associated factors of depression and quality of life in patients with diabetic foot ulcer in Hospital Tengku Ampuan Afzan

Tze, Lin Chan and Zainal, Nor Zuraida and Musa, Ramli (2016) The associated factors of depression and quality of life in patients with diabetic foot ulcer in Hospital Tengku Ampuan Afzan. In: 20th Malaysian Conference of Psychological Medicine (MCPM 2016), 2nd-4th June 2016, Kuala Lumpur. (Unpublished)

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Abstract

Introduction: Diabetic foot complications are one of the common causes of lower extremity amputations. Furthermore, diabetic patients with foot ulcer have high hospitalization rates as compared with those without foot complications. Diabetic foot ulcer patients with comorbid depression have high morbidity and mortality as well as poor quality of life. However, there is limited study available in Malaysia. Objective: The primary aim was to determine the prevalence of depression in patients with diabetic foot ulcer in Hospital Tengku Ampuan Afzan and to determine the sociodemographic and clinical factors associated with depression in diabetic foot ulcer patients. The study was also to determine the quality of life and social support among diabetic foot ulcer patients and compared between the depressed and non depressed diabetic foot patients. Method: This was a cross sectional study where a total of 150 diabetic foot ulcer patients were recruited. Sociodemographic data and clinical variables were determined in diabetic foot ulcer patients. The prevalence of major depressive disorder among the diabetic foot ulcer patients was determined using Mini International Neuropsychiatry Interview (M.I.N.I) and Hospital Anxiety and Depression Scale (HADS). The study also investigated the association between major depressive disorder with clinical and sociodemographic factors of diabetic foot ulcer patients. The Quality of life was assessed using the WHOQOL-BREF and social support was evaluated using Multidimensional Scale of Perceived Social Support (MSPSS). Result: The prevalence of depression in diabetic foot ulcer patients using M.I.N.I was 20.7% and prevalence of depression based on HADS-D with cut off point of ≥8 was 24%. Major depressive disorder was found to be significantly associated with the family history of depression (p=0.015, OR=8.667 ), another chronic medical illnesses (1-2 chronic illnesses p=0.033, OR=5.093; ≥3 chronic medical illnesses p=0.009, OR=13.200), three and more diabetes complication( p=0.025, OR=5.564). In this study, quality of life of diabetic foot ulcer patients with comorbid depression was found lower compared to those without depression. The mean total score for WHOQOL-BREF was 76.6 (SD=8.8) for diabetic foot ulcer patients with depression and 89.2 (SD=10.9) for non depressed group. In this study, the diabetic foot ulcer patients with comorbid depression had perceived overall good social support with mean total score 5.5 (SD=0.98). Conclusion: This study found a high prevalence of depression among the patients with diabetic foot ulcer. The diabetic foot ulcer with comorbid depression had significantly poorer quality of life compared to non depressed group. Medical practitioners should regularly screen high risk group for early detection of depression and improve the quality of life.

Item Type:	Conference or Workshop Item (Plenary Papers)
Additional Information:	5818/50927
Uncontrolled Keywords:	depression,quality of life, patients, diabetic foot ulcer, Hospital Tengku Ampuan Afzan
Subjects:	R Medicine > RC Internal medicine > RC321 Neuroscience. Biological psychiatry. Neuropsychiatry
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine > Department of Psychiatry
Depositing User:	Professor Ramli Musa
Date Deposited:	09 Jun 2016 08:28
Last Modified:	22 May 2018 10:34
URI:	http://irep.iium.edu.my/id/eprint/50927

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