Comparison of dry eye parameters between diabetics and non-diabetics in district of Kuantan, Pahang

Aljarousha, Mohammed and Badarudin, Noor Ezailina and Che Azemin, Mohd Zulfaezal (2016) Comparison of dry eye parameters between diabetics and non-diabetics in district of Kuantan, Pahang. Malaysian Journal of Medical Sciences, 23 (3). pp. 72-77. ISSN 1394-195X E-ISSN 2180-4303

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Abstract

Introduction: Diabetes may affect the human body’s systems and organs, including the eye. Diabetic retinopathy is the 5th leading cause of blindness globally. Diabetic subjects demonstrated dry eye symptoms that were also supported by the low values of the clinical tests. Purpose: This study aimed to compare the dry eye symptoms and signs between diabetics and non-diabetics and tear functions between diabetic subjects with and without dry eye. Methods: This retrospective study was based on the observation of 643 medical files. Using a convenience sampling method, 88 subjects were found to report diabetes mellitus. The information extracted from the files included: date of first examination, age at first visit, gender, past ocular history, systemic disease, symptoms of dry eye disease and details of clinical diagnostic signs. Noncontact lens wearers were excluded. A group of 88, age and gender matched, control subjects were included for this comparison study. Results: The percentage of dry eye symptoms was higher in diabetic subjects (15.9%) compared with non-diabetic subjects (13.6%; p<0.001). The percentage of dry eye symptoms was also higher in diabetics with dry eye (63%) than in diabetics without dry eye (36.9%; p<0.001). Tear break up time was significantly different between diabetics and non-diabetics (p<0.001) and between diabetics with and without dry eye (p=0.046). The corneal staining was significantly different between diabetic subjects with and without dry eye (p=0.028). Conclusion: Dry eye symptoms were significantly associated with diabetics. Tear break up time was significantly shorter in diabetics with dry eye compared to diabetics without dry eye.

Item Type:	Article (Journal)
Additional Information:	6235/50603
Uncontrolled Keywords:	Diabetes mellitus, dry eye syndromes, cornea, tears, sign and symptoms
Subjects:	R Medicine > RE Ophthalmology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Allied Health Sciences > Department of Optometry and Visual Science Kulliyyah of Allied Health Sciences
Depositing User:	Dr. Mohd Zulfaezal Che Azemin
Date Deposited:	13 Jun 2016 12:08
Last Modified:	30 Jun 2022 15:48
URI:	http://irep.iium.edu.my/id/eprint/50603

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