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Adrenal insufficiency resulting from Histoplasmosis infiltration in an immunocompetent patient

Shahar, Mohammad Arif and Ab Wahab, Norasyikin and AbAziz, Aini and Omar , Ahmad Marzuki and Mohd Rusly, Noor Ashikin and Kamaruddin, Nor Azmi (2015) Adrenal insufficiency resulting from Histoplasmosis infiltration in an immunocompetent patient. Brunei International Medical Journal, 11 (5). pp. 261-264. ISSN 2079-3146 (O), 1560-5876 (P)

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Histoplasmosis usually affects immunocompromised patients. Histoplasmosis infiltration to the adrenal in an immunocompetent host is rare, more so those who presented with adrenal insufficiency. We report a case of 54-year-old previously fit and healthy man who presented with chronic headache of two months duration that was associated with loss of appetite and weight-loss. He had hypotension, hyponatremia, relative hyperkalemia with morning cortisol of 160 nmol/L. Computed tomography of the adrenals showed bilateral enlarged adrenal glands and biopsy confirmed histoplasmosis infiltration. Treatment successfully ameliorate symptoms of hypocortisolism. This case illustrates that immunocompetent patient is still susceptible to adrenal histoplasmosis resulting in adrenal insufficiency.

Item Type: Article (Case Report)
Additional Information: 5471/49649
Uncontrolled Keywords: Adrenal insufficiency, histoplasmosis, immunocompetent, adrenal masses
Subjects: R Medicine > R Medicine (General)
R Medicine > RC Internal medicine
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Medicine > Department of Internal Medicine
Depositing User: Dr Mohammad Arif Shahar
Date Deposited: 19 Feb 2016 13:56
Last Modified: 30 Nov 2017 10:35
URI: http://irep.iium.edu.my/id/eprint/49649

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