Activation of mouse oocytes and in vitro embryo enhancing potential of Nigella Sativa

Abdul Rahman, Suzanah and Abdul Rahman, Mohd Rahimi Ashraf and Abdul Samat, Nadia Hanis and Basha, Sadak (2015) Activation of mouse oocytes and in vitro embryo enhancing potential of Nigella Sativa. In: The 2nd International Conference on Advances in Medical Science (ICAMS), 14-16 April 2015, Concorde Hotel, Kuala Lumpur. (Unpublished)

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Abstract

Objective: Aim of the present study is to optimize the development of the mouse embryo with addition of different concentrations of Nigella sativa extract in the culture. Methods: In this study, three different concentrations of Nigella sativa supplementation were used to assist in the enhancement of embryo development. G-1 media was used as a control (Group I). Groups II, III and IV were modified with the addition of Nigella sativa at low dose (5%), moderate dose (10%) and high dose (15%) respectively. Results: Results showed an increase in the number of oocytes that successfully developed into morula and blastocyst after supplementation with three different concentrations of Nigella sativa in the embryo medium. Conclusions: The outcome of the study indicated that Nigella sativa supplementation at a moderate concentration may help in the optimization of mouse embryo culture leading to an increase in the number of morulas and blastocysts.

Item Type:	Conference or Workshop Item (Slide Presentation)
Additional Information:	4493/49392
Uncontrolled Keywords:	Mouse oocytes,in vitro embryo,nigella sativa
Subjects:	R Medicine > RM Therapeutics. Pharmacology > RM300 Drugs and their action
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Allied Health Sciences > Department of Biomedical Science (Effective:1st July 2011)
Depositing User:	Prof. Dr. Suzanah Abdul Rahman
Date Deposited:	03 May 2017 13:17
Last Modified:	03 May 2017 13:17
URI:	http://irep.iium.edu.my/id/eprint/49392

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