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Simulation of an hybrid blood cells micro-separator

Aissa, Foughalia and Abdul Rahim, Rosminazuin and Nordin, Anis Nurashikin and Ibrahim, Siti Noorjannah (2015) Simulation of an hybrid blood cells micro-separator. In: 2015 IEEE Regional Symposium on Micro and Nanoelectronics (IEEE-RSM2015), 19th-21st August 2015, Kuala Terengganu, Malaysia.

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Abstract

The paper presents numerical analysis in threedimensional (3D) of a hybrid micro-separator that uses magnetophoresis (MAP) and hydrodynamic forces for blood cells separation. The separation between red blood cells (RBC) and white blood cells (WBC) is done by manipulating the differences of their physical and magnetic susceptibilities. The MAP force is induced from ferromagnetic line fabricated on a glass slide while the hydrodynamic force is obtained by a ‘U’ shape microfluidic channel. The analysis was conducted using finite element software, COMSOL Multiphysics®. The particles trajectories, which represent the actual blood cells’ movements on the microseparator, were profiled and show successful separation between RBCs and WBCs by using the MAP and hydrodynamic forces.This study also provides insights of challenges associated with blood separation towards the realization of better diagnostic devices.

Item Type: Conference or Workshop Item (Invited Papers)
Additional Information: 3823/49303
Uncontrolled Keywords: microseparation; microfluidic; magnetophoresis; hydrodynamic; magnetic cell separation
Subjects: T Technology > TA Engineering (General). Civil engineering (General) > TA164 Bioengineering
T Technology > TA Engineering (General). Civil engineering (General) > TA329 Engineering mathematics. Engineering analysis
Kulliyyahs/Centres/Divisions/Institutes: Kulliyyah of Engineering > Department of Electrical and Computer Engineering
Depositing User: Siti Noorjannah Ibrahim
Date Deposited: 09 May 2016 08:03
Last Modified: 25 Sep 2017 02:23
URI: http://irep.iium.edu.my/id/eprint/49303

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