Non Hodgkin lymphoma presenting with adrenal insufficiency and bilateral huge adrenal masses

Huai, Heng Loh and Sukor, Norlela and AW, Norasyikin and M, Norlaila and O, Mohd Rahman and R, Subashini and Shahar, Mohammad Arif and Omar, Ahmad Marzuki and WS, Wan Juani and D, Azura and Ooi, CP and K, Nor Azmi (2014) Non Hodgkin lymphoma presenting with adrenal insufficiency and bilateral huge adrenal masses. Journal of Endocrinology and Metabolism, 4 (1(Sup)). p. 29. ISSN 2229-9572

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Abstract

Adrenal involvement secondary to lymphoma is not commonly seen. We report a case of a 62-year old lady, with underlying hypertension on treatment, but otherwise healthy, presented with adrenal insufficiency with large bilateral adrenal masses, complicated with exudative left pleural effusion. She responded to intravenous hydrocortisone of 50mg tds. Computed tomography (CT) showed large heterogenous bilateral suprarenal masses (Figure 1, Figure 2). There were areas of necrosis with no calcification within the mass. Multiple lymphadenopathy in the abdominal region and mediastinum were noted. Lactate dehydrogenase level was elevated. Fungal and tuberculous cultures were negative. Trucut biopsy of the lesion showed Diffuse Large B cell Lymphoma. She was started on chemotherapy (Rituximab-CHOP). Secondary involvement of bilateral adrenal glands due to widespread lymphoma is not common, with Diffuse Large B cell Lymphoma being the most frequently seen. This is to highlight lymphoma as a possible cause of patient presenting with large bilateral adrenal masses and adrenal insufficiency.

Item Type:	Article (Journal)
Additional Information:	5471/49068
Uncontrolled Keywords:	Non Hodgkin lymphoma
Subjects:	R Medicine > RC Internal medicine
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine > Department of Internal Medicine
Depositing User:	Mrs Noor Azlin Asnam
Date Deposited:	17 Mar 2016 16:02
Last Modified:	12 Jun 2018 11:32
URI:	http://irep.iium.edu.my/id/eprint/49068

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