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The “crazy paving pattern” lung in a pregnant woman

Mohd Firdaus, Mohd Al-Baqlish and How, Soon Hin and Kuan, Yeh Chunn and Ibrahim , Aishah and Abd Ghani, Mohd Rasydan and Chan, Chee Eng and Zakaria, Alik Riasadesa and Satwi, Sapari and Loh, Tien Chi (2015) The “crazy paving pattern” lung in a pregnant woman. Respirology, 20 (S3). p. 81. ISSN 1323-7799

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Pulmonary Alveolar Proteinosis (PAP) is a rare disorder characterized by an abnormal accumulation of a PAS positive material within the alveolar spaces and distal bronchioles. A 29 year old lady in her 29th week of pregnancy presented with prolonged dry cough for two months which was associated with reduced effort tolerance and low grade fever. At presentation she is hypoxic and required oxygen supplement. She was initially treated empirically for tuberculosis but she continued to have worsening hypoxia. A high resolution CT thorax revealed a crazy paving pattern lung which was suggestive of PAP. She delivered a healthy baby at 36 weeks via an elective Caesarean section. Post operatively she underwent diagnostic bronchoalveolar lavage which showed acellular homogenous eosinophilic material which was positive for PAS/PASD and negative for mucin. Therapeutic whole lung lavage was performed and her symptoms and lung function tests improved. In this case report, we will discuss how we made the diagnosis of PAP and share our experience in managing a pregnant woman with this condition.

Item Type: Article (Journal)
Additional Information: 2987/49035 Official Journal of the Asian Pacific Society of Respiratory.
Subjects: R Medicine > RC Internal medicine
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Medicine > Department of Internal Medicine
Depositing User: Mrs Noor Azlin Asnam
Date Deposited: 25 Jan 2016 01:09
Last Modified: 19 Jul 2016 14:36
URI: http://irep.iium.edu.my/id/eprint/49035

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