Anti-cancer potential of agarwood distillate

Abbas, Phirdaous and Hashim, Yumi Zuhanis Has-Yun and Amid, Azura and Mohd. Salleh, Hamzah and Jamal, Parveen and Jaswir, Irwandi (2014) Anti-cancer potential of agarwood distillate. Journal of Pure and Applied Microbiology, 8 (Sp. ed). pp. 871-874. ISSN 0973-7510

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Abstract

Agarwood or Gaharu by definition is the resin impregnated heartwood that produces unique aromatic scent when burnt. Apart from religious rituals and perfumes, agarwood has also been used as traditional medicines leading to the interest of this study which is to screen for anti-cancer properties. In this study, agarwood water distillate (hydrosol) obtained from distillation of agarwood (resin) were screened against MCF-7 cells, which are commonly used as in vitro model for breast cancer and VERO cells (normal cells). Distillate samples were collected, diluted and directly subjected to three anti-cancer screening assays (cell attachment assay, cell viability assay and sulforhodamine B assay). It was found that agarwood distillate possesses anti-cancer activity and exerts no significant effects on normal cells. This warrants further investigation with potential development of alternative remedy against cancer while adding more value to the agarwood industry.

Item Type:	Article (Journal)
Additional Information:	3774/47143
Uncontrolled Keywords:	Agarwood, Gaharu, Distillate, Hydrosol, Anti-cancer, Cell culture.
Subjects:	Q Science > Q Science (General)
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	International Institute for Halal Research and Training (INHART) Kulliyyah of Engineering > Department of Biotechnology Engineering
Depositing User:	DR YUMI ZUHANIS HAS-YUN HASHIM
Date Deposited:	10 Apr 2016 14:41
Last Modified:	23 Jul 2021 10:17
URI:	http://irep.iium.edu.my/id/eprint/47143

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