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Effects of nonsurgical periodontal therapy on high-sensitivity serum c-reactive protein and ESR among Malaysian population with chronic periodontitis

Kamil, Wisam Alaa and Al-Bayati, Lina and Mohamed Ali, Suhaila (2013) Effects of nonsurgical periodontal therapy on high-sensitivity serum c-reactive protein and ESR among Malaysian population with chronic periodontitis. In: International Symposium Osteology Monaco 2013, 2-4 May 2013, Monaco, France .

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Abstract

Objectives: The aim of this study was to assess the outcome of the nonsurgical perio¬dontal treatment in terms of its effect on the hs-CRP and ESR in consecutive subjects diagnosed with chronic periodontitis in order to improve sensitivity and specificity. Methods: 25 systematically healthy subjects diagnosed with chronic periodon¬titis were recruited for the study after obtaining the ethical approval from the ethics committee of the International Islamic University Malaysia. Detailed oral hygiene instruction and standard periodontal therapy were performed. Full clinical periodontal parameters including full mouth plaque scores, bleeding on probing, pocket depth and clinical attachment loss were recorded and re-evaluated 3 months after the treatment completion. Blood samples were collected to determine the high-sensitivity serum C-reactive and the erythrocyte sedimenta¬tion rate at baseline and 3 months after the periodontal treatment. Results: Nonsurgical periodontal therapy resulted in significant reduction in the se¬rum CRP level where the average CRP decreased from 1.8 mg/L at baseline to 1.6 mg/L (p=0.009) after 3 months of periodontal therapy, and the marked improvement in the recorded periodontal parameters were confirmed by the significant decrease in the monitored ESR from 8.3 mm/hr to 5.9 mm/hr (p=0.033). Conclusions: In terms of sensitivity and specificity this study demonstrated that nonsurgical periodontal therapy results in a significant reduction in the serum CRP level and ESR.

Item Type: Conference or Workshop Item (Poster)
Additional Information: 6241/44932
Uncontrolled Keywords: nonsurgical periodontal therapy, high-sensitivity serum, c-reactive protein, Malaysia, chronic periodontitis
Subjects: R Medicine > RK Dentistry
Kulliyyahs/Centres/Divisions/Institutes: Kulliyyah of Dentistry
Depositing User: Dr Wisam Kamil
Date Deposited: 05 Oct 2015 10:27
Last Modified: 05 Oct 2015 10:41
URI: http://irep.iium.edu.my/id/eprint/44932

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