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A hydrogel-actuated microvalve for smart flow control

Lei, Ming and Wan Salim, Wan Wardatul Amani and Siegel, Ronald A. and Ziaie, Babak (2004) A hydrogel-actuated microvalve for smart flow control. In: Proceedings of the IEEE Engineering Medical Biology Society(EMBS), 1st-5th September 2004, San Francisco, CA, USA.

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In this paper, we report on the fabrication and testing of a hydrogel-actuated smart microvalve for biomedical applications. The three-layered microvalve is composed of a stimuli-sensitive ìintelligentî hydrogel sandwiched between a porous silicon membrane and a bossed PDMS flexible diaphragm. The entrapped hydrogel in response to changes in the external physiological stimuli (e.g., pH, glucose, etc.), which diffuses through the porous membrane, swelles and deswelles hence deflecting the flexible PDMS diaphragm and controlling the closure and opening of the microvalve inlet. A microvalve incorporating a 155µm thick hydrogel (poly(methacrylic acid-co-acrylamide), mAA-co-AAm) has a response time of 3.6 min to a sudden pH change (pH=3 to pH=7).

Item Type: Conference or Workshop Item (Plenary Papers)
Additional Information: 7116/44329
Uncontrolled Keywords: Hydrogel, pH-sensitive, microvalve, flow control, microfluidics, PDMS
Subjects: Q Science > QC Physics
T Technology > T Technology (General)
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Engineering > Department of Biotechnology Engineering
Kulliyyah of Engineering
Depositing User: Dr Wan Wardatul Amani Wan Salim
Date Deposited: 11 Feb 2020 10:05
Last Modified: 11 Feb 2020 10:05
URI: http://irep.iium.edu.my/id/eprint/44329

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