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Measurement of blood flow velocity waveforms in the carotid, brachial and femoral arteries during postural change

Noor Azmi, Azran Azhim and M., Katai and M., Akutagawa and Y., Hirao and K., Yoshizaki and S., Obara and M., Nomura and H., Tanaka and H., Yamaguchi and Y., Kinouchi (2006) Measurement of blood flow velocity waveforms in the carotid, brachial and femoral arteries during postural change. In: International Conference on Biomedical and Pharmaceutical Engineering, ICBPE 2006., 11-14 Dec. 2006, Singapore.

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The purpose of this study was to measure blood flow velocities in carotid, brachial and femoral arteries simultaneously during passive postural change using our developed telemetry measurement system. This system was implemented with synchronized measurement of electrocardiogram (ECG). The velocity waveforms and ECG were continuously measured in six putatively healthy young subjects for 130 s during passive postural changes in supine and 90 degrees head-up-tilt (HUT), respectively. Peak systolic SI and end-diastolic d velocities were obtained from the velocity waveforms in 3 arteries, and using these velocities as an index of d/Sl to assess the velocity waveforms during the postural change. The velocity waveforms of 3 arteries, heart rate (HR), and blood pressure (BP) were assessed for 20 s at the stages of postural change. As a result, HTJT-induced increase in HR was more pronounced in the young subjects. The index of d/Sl in carotid was significantly decreased during HUT, whereas the index of that in brachial and femoral arteries were significantly increased. There was significant increase in diastolic BP but, a non significant change in systolic BP to tilt. The decreased of the blood flow index in the carotid artery was expected to be the effect of cerebral autoregulation (CA) to control blood flow to the brain. In contrast, the blood flow in the brachial and femoral was more influenced of venous pressure (VP) in postural change. In conclusion, HUT produced larger changes in the 3 arteries, particularly in brachial and femoral, and also in HR and diastolic BP. This study demonstrated that synchronized measurement of blood flow velocity waveforms in carotid, brachial, and femoral in HUT postural change using our telemetry measurement device was attainable. Thus, this method could prove to be a useful tool for investigating cardiovascular disease (CD) risk with further research and development.

Item Type: Conference or Workshop Item (Full Paper)
Additional Information: 7380/44093
Uncontrolled Keywords: blood flow velocity waveforms, synchronized measurement, head-up-tilt postural changes, venous pressure, cerebral autoregulation
Subjects: T Technology > TP Chemical technology > TP248.13 Biotechnology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Science > Department of Biotechnology
Depositing User: Ir Dr Azran Azhim Noor Azmi
Date Deposited: 17 Aug 2015 11:16
Last Modified: 17 Aug 2015 11:16
URI: http://irep.iium.edu.my/id/eprint/44093

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