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Hybrid metallic nanoparticles: enhanced bioanalysis and biosensing via carbon nanotubes, graphene, and organic conjugation

Daniele, Michael A. and Pedrero, Maria and Burrs, Stephanie and Chaturvedi, Prachee and Wan Salim, Wan Wardatul Amani and Kuralay, Filiz and Campuzano-Ruiz, Susana and McLamore, Eric and Claussen, Jonathan C. and Cargill, Allison A. and Ding, Shaowei and Claussen, Jonathan C. (2015) Hybrid metallic nanoparticles: enhanced bioanalysis and biosensing via carbon nanotubes, graphene, and organic conjugation. In: Nanobiosensor and Nanobioanalyses. Springer, Japan, pp. 137-166. ISBN 978-4-431-55189-8

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Composite materials, incorporating noble metal and metal oxide nanoparticles, have attracted much interest as active substrates for biosensor electronics. These nanoparticles provide a viable microenvironment for biomolecule immobilization by retaining their biological activity with desired orientation and for facilitating transduction of the biorecognition event. Herein, we discuss various methods for fabrication of metal and metal oxide nanoparticle composite materials and their applications in different electrochemical biosensors. The materials are organized by the corresponding component with the nanoparticles, i.e. carbon-based composites, polymers, and DNA. The performance of hybrids is compared and examples of biosensing apparatus are discussed. In all cases, the engineering of morphology, particle size, effective surface area, functionality, adsorption capability, and electron-transfer properties directly impact the resultant biosensing capabilities. Ultimately, these attractive features of metal and metal-oxide hybrid materials are expected to find applications in the next generation of smart biosensors.

Item Type: Book Chapter
Additional Information: 7116/43889
Uncontrolled Keywords: Carbon nanotubes – DNA – Graphene – Metal oxide nanoparticles – Metallic nanoparticles – Polymer
Subjects: Q Science > QD Chemistry
T Technology > TK Electrical engineering. Electronics Nuclear engineering
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Engineering
Depositing User: Dr Wan Wardatul Amani Wan Salim
Date Deposited: 08 Jan 2016 09:56
Last Modified: 14 Dec 2016 08:46
URI: http://irep.iium.edu.my/id/eprint/43889

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