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Assessment of first derivative of doppler blood flow velocity in vascular aging

Zulaika, H. and Noor Azmi, Azran Azhim and Saleh, M. and Baghepour, P. and Kinouchi, Y. and Ibrahim, F. (2014) Assessment of first derivative of doppler blood flow velocity in vascular aging. In: » The 15th International Conference on Biomedical Engineering , 4-7 December 2013, Singapore.

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The aim of this study is to determine the first derivative of blood flow velocity (FDBFV) in common carotid artery (CCA) in order to evaluate cardiovascular functions. The extracted derivative of the velocity is suggested the acceleration waves which able to provide an aging index (AGI) in the cardiovascular system. In the study, acceleration wave derived from FDBFV consist of a, b, c, d, e and f waves which represent the initial positive, early negative, re-increasing, late re-decreasing, diastolic positive waves and diastolic negative waves, respectively. The FDBFV waveforms of 227 healthy volunteers are statistically analyzed in the study. Pearson’s correlation analysis is used to determine the relationship between all variables and factors on the selected hemodynamic data. In the study, there are significant difference (r=0.727, p<0.001) of AGI in FDBFV. We found that f wave in FDBFV waveform shows strong correlation (p< 0.001) to blood pressure. In conclusion, the potential of FDBFV in CCA is an effective method to evaluate the vascular aging.

Item Type: Conference or Workshop Item (Full Paper)
Additional Information: 7380/43807 ISBN : 978-3-319-02913-9_18
Uncontrolled Keywords: Common carotid artery, vascular aging and cardiovascular.
Subjects: T Technology > TP Chemical technology > TP248.13 Biotechnology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Science > Department of Biotechnology
Depositing User: Ir Dr Azran Azhim Noor Azmi
Date Deposited: 28 Jul 2015 14:56
Last Modified: 04 Mar 2016 08:41
URI: http://irep.iium.edu.my/id/eprint/43807

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