Antimicrobial effect of Baccaurea angulata fruit extracts against human pathogenic microorganisms

Momand, Lailuma and Zakaria, Robaiza and Mikail, Maryam Abimbola and Kamal, Tara and Ibrahim, Muhammad and Abdul Wahab, Ridhwan (2014) Antimicrobial effect of Baccaurea angulata fruit extracts against human pathogenic microorganisms. Merit Research Journal of Medicine and Medical Sciences, 2 (10). pp. 229-237. ISSN 2354-323X

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Abstract

The research application for drugs and food supplements derived from plants extracts have increased in recent years. Plants extract and their constituents are recognized to be safe, either because of their traditional use without any documented detrimental impact or because of dedicated toxicological studies. The potential of higher plants as a source for new drugs is largely unexplored. Thus, a systematic investigation was undertaken to screen for antibacterial activity from Baccaurea angulata. Plant that belongs to the family is used as food as well as treatment of infectious diseases such as diarrhoea, skin infections and gonorrhoea. The anti-microbial activity of the B. angulata fruit extracts have revealed different antimicrobial properties, that vary between three parts (whole fruit, fruit skin, and berry), three solvents (methanol, ethanol and aqueous), using agar well diffusion, and microdilution methods and different pathogens (Streptococcus pneumoniae, Staphylococcus epidermidis, Klebsiella pneumoniae and Pseudomonas aeruginosa). The highest observed antimicrobial activity was in ethanol extract of fruit skin using agar well diffusion against S. pneumoniae. Among tested Gram negative bacteria, K. pneumoniae was the most susceptible bacterium which showed the highest bacteriostatic and bactericidal activity using microdilution method. All parts of fruit extracts poses the antimicrobial activities against all human pathogenic microorganisms used in this study.

Item Type:	Article (Journal)
Additional Information:	4998/43509
Uncontrolled Keywords:	Antimicrobial activity, Baccaurea angulata, Minimum inhibitory concentration (MIC), Minimum bactericidal concentration (MBC)
Subjects:	Q Science > QK Botany Q Science > QR Microbiology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Allied Health Sciences > Department of Biomedical Science (Effective:1st July 2011)
Depositing User:	Dr Ridhwan Abdul Wahab
Date Deposited:	24 Jun 2015 15:09
Last Modified:	03 Jan 2018 17:26
URI:	http://irep.iium.edu.my/id/eprint/43509

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