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Antimicrobial activity of mangrove plant (Lumnitzera littorea)

Saad, Shahbudin and Bakhtiar, M. Taher and Darnis, Deny Susanti and Qaralleh, Haitham and Abdul Rahim, Nurul Afifah (2011) Antimicrobial activity of mangrove plant (Lumnitzera littorea). Asian Pacific Journal of Tropical Medicine, 4 (7). pp. 523-525. ISSN 1995-7645

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Abstract

Objective To investigate the antimicrobial activities of n-hexane, ethyl acetate and methanol extracts of the leaves of Lumnitzera littorea (L. littorea) against six human pathogenic microbes. Methods The antimicrobial activity was evaluated using disc diffusion and microdilution methods. Results The antimicrobial activities of the crude extracts were increased with increasing the concentration. It is clear that n-hexane extract was the most effective extract. Additionally, Gram positive Bacillus cereus (B. cereus) appear to be the most sensitive strain while Pseudomonas aeruginosa (P. aeruginosa) and the yeast strains (Candida albicans (C. albicans) and Cryptococcus neoformans (C. neoformans)) appear to be resistance to the tested concentrations since no inhibition zone was observed. The inhibition of microbial growth at concentration as low as 0.04 mg/mL indicated the potent antimicrobial activity of L. littorea extracts. Conclusions The obtained results are considered sufficient for further study to isolate the compounds responsible for the activity and suggesting the possibility of finding potent antibacterial agents from L. littorea extracts.

Item Type: Article (Journal)
Additional Information: 5605/4339
Uncontrolled Keywords: Antimicrobial, Lumnitzera littorea, Mangroves
Subjects: R Medicine > RS Pharmacy and materia medica
Kulliyyahs/Centres/Divisions/Institutes: Kulliyyah of Pharmacy > Department of Pharmaceutical Technology
Kulliyyah of Science > Department of Biotechnology
Kulliyyah of Science > Institute of Oceanography and Maritime Studies
Depositing User: Dr Muhammad Taher
Date Deposited: 28 Oct 2011 16:20
Last Modified: 12 Dec 2011 14:39
URI: http://irep.iium.edu.my/id/eprint/4339

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