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Immunological Changes in Secondary Sjogran Syndrome (Comparative Study)

Mustafa Al-Ahmad, Basma Ezzat and Mustafa, Nazih Shaban and Kashmola, Muhanad Ali Hamdon (2015) Immunological Changes in Secondary Sjogran Syndrome (Comparative Study). Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 119 (3). e126. ISSN 2212-4411

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Abstract

Objective This study was designed to evaluate the immunological changes and its existence for early diagnosis and proper management of disease. Study Design 56 patients with RA accompanied by sSS where included in this study and compared to 60 RA patients without sSS.Schirmers test, blood tests and search for auto antibodies was done for all patients in both groups. Schirmers, blood tests and search for antinuclear antibody was done for all patients in both groups, with the measurement of salivary flow rate. Results Schirmers test was positive in all sSS and negative in all RA patients, whilst salivary flow rate was reduced in all sSS. Latex fixation test, ANA, Anti Ro and Anti La were reported significantly higher in sSS (p<0.01) Conclusions Secondary Sjogrens syndrome had a significantly positive rheumatoid factor, antinuclear antibody, anti Ro (SS-A) and anti La (SS-B) compared to rheumatoid patients without Sjogrens syndrome.

Item Type: Article (Journal)
Additional Information: 5816/42214
Uncontrolled Keywords: Immunological Changes, Secondary Sjogran Syndrome
Subjects: R Medicine > R Medicine (General)
Kulliyyahs/Centres/Divisions/Institutes: Kulliyyah of Dentistry
Depositing User: Dr Basma Al-Ahmad
Date Deposited: 24 Feb 2015 17:28
Last Modified: 24 Nov 2015 07:57
URI: http://irep.iium.edu.my/id/eprint/42214

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