Screening of aphrodisiac property in sea slug, aplysia dactylomela

Hashim, Ridzwan and Mohd Roslan, Noor Atika Elliyana and Zulkipli, Farah Hanis and Mohd Daud, Jamaluddin (2014) Screening of aphrodisiac property in sea slug, aplysia dactylomela. Asian Pacific Journal of Tropical Medicine, 7 (1). S150-S154. ISSN 1995-7645

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Abstract

Objective: To evaluate the aphrodisiac property of Aplysia dactylomela (A. dactylomelan), locally known as 'dugu-dugu', which is one of the sea slug species. Methods: Two types of extractions were used: aqueous and lipid. Three doses of each A. dactylomelan extract, respectively; 50, 100, 200 mg/kg were administered (i.p.) to male mice for mounting behavior test. Sildenafil citrate or Viagra(R) (5 mg/kg) being positive control while negative control received saline solution. Results: The animals treated with lipid extract at the respective dose exhibited mounting behavior, but the mounting frequency decreased at higher doses (100 and 200 mg/kg). However, all doses of aqueous extract did not show any mounting behavior. Meanwhile, in all doses of lipid extracts administered displayed significant difference 9P<0.05) from the positive control. Despite this, only the lipid extract of 50 mg/kg showed significant difference (P<0.05) with negative control. This signifies that lipid extracts especially in dose 50 mg/kg have a substantial effect of aphrodisiac property. In addition, the presence of steroids was detected in the phytochemical screening of lipid extract. Conclusions: The findings from this study provides preliminary scientific evidence that A. dactylomela could be used as an alternative medication of natural product for promoting sexual activity in men.

Item Type:	Article (Journal)
Additional Information:	5465/42093
Uncontrolled Keywords:	Aplysia dactylomela extract,Aphrodisiac,Mounting frequency, Sildenafil citrate
Subjects:	R Medicine > R Medicine (General)
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Science > Department of Chemistry
Depositing User:	Dr Jamaluddin Mohd Daud
Date Deposited:	24 Feb 2015 11:01
Last Modified:	25 Sep 2017 18:22
URI:	http://irep.iium.edu.my/id/eprint/42093

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