Tissue engineering of articular cartilage: from bench to bed-side

Abdul Rahman, Rozlin and Ahmad Radzi, Muhammad Aa'zamuddin and Mohamad Syukri, Norhamiza and Md Nazir, Noorhidayah and Sha'ban, Munirah (2014) Tissue engineering of articular cartilage: from bench to bed-side. Tissue Engineering and Regenerative Medicine, 12 (1). pp. 1-11. ISSN 1738-2696 E-ISSN 2212-5469

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Abstract

Degeneration or defect of articular cartilage is a major predicament and if it is left untreated, it may lead to progressive damage and disability affecting every one disregard of their age. Although nonsurgical management of articular cartilage injury has remained largely the same over many years, surgical treatment keeps on evolving. Restorative techniques, mainly the cell-based therapies and autologous or allograft transplants continue to expand, giving surgeons more options for biologic reconstruction of the articular surfaces. Hence the field of articular cartilage tissue engineering which seeks to repair, restore and improve injured or diseased articular cartilage functionality has aroused deep interest and holds great potential for improving articular cartilage therapy. However despite this great evolution, therapeutic uncertainty in the restoration of damaged cartilage using tissue engineering approaches still remains unclear for the surgeon treating patients to make evidence-based decisions. This paper will give a general idea to different level of audiences in understanding the concept of tissue engineering from bench to bed-side regarding recent developments in this exciting field.

Item Type:	Article (Journal)
Additional Information:	6006/41407 Corresponding author: Dr. Munirah Sha'ban (Staff no. 6006)
Uncontrolled Keywords:	tissue engineering, articular cartilage, cartilage regeneration, regenerative medicine, bench to bed-side
Subjects:	R Medicine > R Medicine (General)
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Allied Health Sciences > Department of Biomedical Science (Effective:1st July 2011)
Depositing User:	Munirah Sha'ban
Date Deposited:	13 Feb 2015 11:06
Last Modified:	20 Sep 2017 15:32
URI:	http://irep.iium.edu.my/id/eprint/41407

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